![](/images/graphics-bg.png)
Clinical Features and Drug Characteristics of Patients with Generalized Fixed Drug Eruption in the West of Iran (2005–2014)
Joint Authors
Rezaei, Mansour
Kavoussi, Reza
Derakhshandeh, Katayoun
Moradi, Alireza
Rashidian, Harif
Ebrahimi, Ali
Kavoussi, Hossein
Source
Dermatology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-10
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Generalized fixed drug eruption is a specific variant of fixed drug eruption with multifocal lesions.
Diagnosis of this drug reaction is straightforward, but occasionally recognition of the causative drug is not possible.
This study was aimed at evaluating the clinical features and culprit drugs in generalized fixed drug eruptions in the west of Iran.
Method.
This cross-sectional study was carried out on 30 patients with criteria of generalized fixed drug eruption over 9 years.
Demographic, clinical, and drug intake information were collected.
Results.
Out of 30 patients (17 females and 13 males) with the mean age of 26.67 ± 10.21 years, 28 (93.3%) and 2 (6.7%) cases had plaque and bullous clinical presentation, respectively.
Upper limbs were the most common (90%) site of involvement.
The antibiotic group, especially cotrimoxazole (26.1%), was reported to be the most common offending drug, but the causative drug was not determined in 7 (23.3%) patients.
Conclusion.
Many cases of generalized fixed drug eruption firstly presented as limited lesions and led to generalized lesion due to repeated intake of the causative drug.
No causative drug was found in some patients, which might be associated with concurrent intake of several drugs, multiple FDE, and peculiarity of the patch test.
American Psychological Association (APA)
Kavoussi, Hossein& Rezaei, Mansour& Derakhshandeh, Katayoun& Moradi, Alireza& Ebrahimi, Ali& Rashidian, Harif…[et al.]. 2015. Clinical Features and Drug Characteristics of Patients with Generalized Fixed Drug Eruption in the West of Iran (2005–2014). Dermatology Research and Practice،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1061097
Modern Language Association (MLA)
Kavoussi, Hossein…[et al.]. Clinical Features and Drug Characteristics of Patients with Generalized Fixed Drug Eruption in the West of Iran (2005–2014). Dermatology Research and Practice No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1061097
American Medical Association (AMA)
Kavoussi, Hossein& Rezaei, Mansour& Derakhshandeh, Katayoun& Moradi, Alireza& Ebrahimi, Ali& Rashidian, Harif…[et al.]. Clinical Features and Drug Characteristics of Patients with Generalized Fixed Drug Eruption in the West of Iran (2005–2014). Dermatology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1061097
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061097