Antimicrobial Activity of the Essential Oil of Plectranthus neochilus against Cariogenic Bacteria
Joint Authors
Groppo, Milton
Cunha, Wilson Roberto
Martins, C. H. G.
Crotti, Antônio Eduardo Miller
Crevelin, Eduardo José
Caixeta, Soraya Carolina
Dias, Herbert Júnior
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
This work used the broth microdilution method to investigate the antimicrobial activity of the essential oil obtained from the leaves of Plectranthus neochilus (PN-EO) against a representative panel of oral pathogens.
We assessed the antimicrobial activity of this oil in terms of the minimum inhibitory concentration (MIC).
PN-EO displayed moderate activity against Enterococcus faecalis (MIC = 250 μg/mL) and Streptococcus salivarus (MIC = 250 μg/mL), significant activity against Streptococcus sobrinus (MIC = 62.5 μg/mL), Streptococcus sanguinis (MIC = 62.5 μg/mL), Streptococcus mitis (MIC = 31.25 μg/mL), and Lactobacillus casei (MIC = 31.25 μg/mL), and interesting activity against Streptococcus mutans (MIC = 3.9 μg/mL).
GC-FID and GC-MS helped to identify thirty-one compounds in PN-EO; α-pinene (1, 14.1%), β-pinene (2, 7.1%), trans-caryophyllene (3, 29.8%), and caryophyllene oxide (4, 12.8%) were the major chemical constituents of this essential oil.
When tested alone, compounds 1, 2, 3, and 4 were inactive (MIC > 4000 μg/mL) against all the microorganisms.
These results suggested that the essential oil extracted from the leaves of Plectranthus neochilus displays promising activity against most of the evaluated cariogenic bacteria, especially S.
mutans.
American Psychological Association (APA)
Crevelin, Eduardo José& Caixeta, Soraya Carolina& Dias, Herbert Júnior& Groppo, Milton& Cunha, Wilson Roberto& Martins, C. H. G.…[et al.]. 2015. Antimicrobial Activity of the Essential Oil of Plectranthus neochilus against Cariogenic Bacteria. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1061136
Modern Language Association (MLA)
Crevelin, Eduardo José…[et al.]. Antimicrobial Activity of the Essential Oil of Plectranthus neochilus against Cariogenic Bacteria. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1061136
American Medical Association (AMA)
Crevelin, Eduardo José& Caixeta, Soraya Carolina& Dias, Herbert Júnior& Groppo, Milton& Cunha, Wilson Roberto& Martins, C. H. G.…[et al.]. Antimicrobial Activity of the Essential Oil of Plectranthus neochilus against Cariogenic Bacteria. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1061136
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061136