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The Anti-Inflammatory Actions of Auricular Point Acupressure for Chronic Low Back Pain
Joint Authors
Glick, Ronald M.
Chien, Lung Chang
Lin, Wei-Chun
Yeh, Chao Hsing
Morone, Natalia E.
Albers, Kathryn M.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-11
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
Auricular point acupressure (APA) is a promising treatment for pain management.
Few studies have investigated the physiological mechanisms of APA analgesics.
Method.
In this pilot randomized clinical trial (RCT), a 4-week APA treatment was used to manage chronic low back pain (CLBP).
Sixty-one participants were randomized into a real APA group (n=32) or a sham APA group (n=29).
Blood samples, pain intensity, and physical function were collected at baseline and after 4 weeks of treatment.
Results.
Subjects in the real APA group reported a 56% reduction of pain intensity and a 26% improvement in physical function.
Serum blood samples showed (1) a decrease in IL-1β, IL-2, IL-6, and calcitonin gene-related peptide [CGRP] and (2) an increase in IL-4.
In contrast, subjects in the sham APA group (1) reported a 9% reduction in pain and a 2% improvement in physical function and (2) exhibited minimal changes of inflammatory cytokines and neuropeptides.
Statistically significant differences in IL-4 and CGRP expression between the real and sham APA groups were verified.
Conclusion.
These findings suggest that APA treatment affects pain intensity through modulation of the immune system, as reflected by APA-induced changes in serum inflammatory cytokine and neuropeptide levels.
American Psychological Association (APA)
Lin, Wei-Chun& Yeh, Chao Hsing& Chien, Lung Chang& Morone, Natalia E.& Glick, Ronald M.& Albers, Kathryn M.. 2015. The Anti-Inflammatory Actions of Auricular Point Acupressure for Chronic Low Back Pain. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1061140
Modern Language Association (MLA)
Lin, Wei-Chun…[et al.]. The Anti-Inflammatory Actions of Auricular Point Acupressure for Chronic Low Back Pain. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1061140
American Medical Association (AMA)
Lin, Wei-Chun& Yeh, Chao Hsing& Chien, Lung Chang& Morone, Natalia E.& Glick, Ronald M.& Albers, Kathryn M.. The Anti-Inflammatory Actions of Auricular Point Acupressure for Chronic Low Back Pain. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1061140
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061140