A Systematic Review of Rhubarb (a Traditional Chinese Medicine) Used for the Treatment of Experimental Sepsis
Joint Authors
Lai, Fang
Zhang, Yan
Xie, Dong-ping
Mai, Shu-tao
Weng, Yan-na
Du, Jiong-dong
Wu, Guang-ping
Zheng, Jing-xia
Han, Yun
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-03
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Sepsis is a global major health problem in great need for more effective therapy.
For thousands of years, Rhubarb had been used for various diseases including severe infection.
Pharmacological studies and trials reported that Rhubarb may be effective in treating sepsis, but the efficacy and the quality of evidence remain unclear since there is no systematic review on Rhubarb for sepsis.
The present study is the first systematic review of Rhubarb used for the treatment of experimental sepsis in both English and Chinese literatures by identifying 27 studies from 7 databases.
It showed that Rhubarb might be effective in reducing injuries in gastrointestinal tract, lung, and liver induced by sepsis, and its potential mechanisms might include reducing oxidative stress and inflammation, ameliorating microcirculatory disturbance, and maintaining immune balance.
Yet the positive findings should be interpreted with caution due to poor methodological quality.
In a word, Rhubarb might be a promising candidate that is worth further clinical and experimental trials for sepsis therapy.
American Psychological Association (APA)
Lai, Fang& Zhang, Yan& Xie, Dong-ping& Mai, Shu-tao& Weng, Yan-na& Du, Jiong-dong…[et al.]. 2015. A Systematic Review of Rhubarb (a Traditional Chinese Medicine) Used for the Treatment of Experimental Sepsis. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1061159
Modern Language Association (MLA)
Lai, Fang…[et al.]. A Systematic Review of Rhubarb (a Traditional Chinese Medicine) Used for the Treatment of Experimental Sepsis. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1061159
American Medical Association (AMA)
Lai, Fang& Zhang, Yan& Xie, Dong-ping& Mai, Shu-tao& Weng, Yan-na& Du, Jiong-dong…[et al.]. A Systematic Review of Rhubarb (a Traditional Chinese Medicine) Used for the Treatment of Experimental Sepsis. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1061159
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061159