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Topical Anti-Inflammatory Activity of Oil from Tropidurus hispidus (Spix, 1825)
Joint Authors
Almeida, Waltécio de Oliveira
Santos, Israel J. M.
Leite, Gerlania O.
Campos, Adriana Rolim
Freita, Francisco Ronaldo V.
Nunes, Maria Janeth H.
Alves, Romulo Romeu da Nobrega
Costa, José Galberto Martins da
de Menezes, Irwin Rose Alencar
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-18
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Tropidurus hispidus has been used in traditional medicine in several regions of Northeastern Region of Brazil.
Its medicinal use involves the treatment of diseases such as warts, sore throat, tonsillitis, chicken pox, varicella, measles, asthma, alcoholism, and dermatomycosis.
The present study evaluated the topical anti-inflammatory activity of Tropidurus hispidus fat in treating ear edema in an animal model.
Oil from T.
hispidus (OTH) was evaluated on its effect against experimental inflammation in mice.
OTH was extracted from body fat located in the ventral region of Tropidurus hispidus using hexane as a solvent.
We used the model of mouse ear edema induced by phlogistic agents, croton oil (single and multiple applications), arachidonic acid, phenol, capsaicin, and histamine, applied into the right ears of animals pretreated with acetone (control), dexamethasone, or OTH.
OTH inhibited the dermatitis induced by all noxious agents, except capsaicin.
This effect may be related to the fatty acids present in OTH.
American Psychological Association (APA)
Santos, Israel J. M.& Leite, Gerlania O.& Costa, José Galberto Martins da& Alves, Romulo Romeu da Nobrega& Campos, Adriana Rolim& de Menezes, Irwin Rose Alencar…[et al.]. 2015. Topical Anti-Inflammatory Activity of Oil from Tropidurus hispidus (Spix, 1825). Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1061165
Modern Language Association (MLA)
Santos, Israel J. M.…[et al.]. Topical Anti-Inflammatory Activity of Oil from Tropidurus hispidus (Spix, 1825). Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1061165
American Medical Association (AMA)
Santos, Israel J. M.& Leite, Gerlania O.& Costa, José Galberto Martins da& Alves, Romulo Romeu da Nobrega& Campos, Adriana Rolim& de Menezes, Irwin Rose Alencar…[et al.]. Topical Anti-Inflammatory Activity of Oil from Tropidurus hispidus (Spix, 1825). Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1061165
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061165