Evaluation of an Epitypified Ophiocordyceps formosana (Cordyceps s.l.) for Its Pharmacological Potential
Joint Authors
Tai, Yu-Ling
Shen, Tang-Long
Wang, Yen-Wen
Hong, Tzu-Wen
Wang, Ying-Jing
Tsai, Sheng-Hong
Lien, Pham Thi Kim
Chou, Tzu-Ho
Lai, Jui-Ya
Chu, Richard
Irie, Kenji
Li, Tsai-Kun
Tzean, Shean-Shong
Ding, Shih-Torng
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-15
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
The substantial merit of Cordyceps s.l.
spp.
in terms of medicinal benefits is largely appreciated.
Nevertheless, only few studies have characterized and examined the clinical complications of the use of health tonics containing these species.
Here, we epitypified C.
formosana isolates that were collected and characterized as Ophiocordyceps formosana based on morphological characteristics, molecular phylogenetic analyses, and metabolite profiling.
Thus, we renamed and transferred C.
formosana to the new protologue Ophiocordyceps formosana (Kobayasi & Shimizu) Wang, Tsai, Tzean & Shen comb.
nov.
Additionally, the pharmacological potential of O.
formosana was evaluated based on the hot-water extract from its mycelium.
The relative amounts of the known bioactive ingredients that are unique to Cordyceps s.l.
species in O.
formosana were found to be similar to the amounts in O.
sinensis and C.
militaris, indicating the potential applicability of O.
formosana for pharmacological uses.
Additionally, we found that O.
formosana exhibited antioxidation activities in vitro and in vivo that were similar to those of O.
sinensis and C.
militaris.
Furthermore, O.
formosana also displayed conspicuously effective antitumor activity compared with the tested Cordyceps s.l.
species.
Intrinsically, O.
formosana exhibited less toxicity than the other Cordyceps species.
Together, our data suggest that the metabolites of O.
formosana may play active roles in complementary medicine.
American Psychological Association (APA)
Wang, Yen-Wen& Hong, Tzu-Wen& Tai, Yu-Ling& Wang, Ying-Jing& Tsai, Sheng-Hong& Lien, Pham Thi Kim…[et al.]. 2015. Evaluation of an Epitypified Ophiocordyceps formosana (Cordyceps s.l.) for Its Pharmacological Potential. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1061224
Modern Language Association (MLA)
Wang, Yen-Wen…[et al.]. Evaluation of an Epitypified Ophiocordyceps formosana (Cordyceps s.l.) for Its Pharmacological Potential. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1061224
American Medical Association (AMA)
Wang, Yen-Wen& Hong, Tzu-Wen& Tai, Yu-Ling& Wang, Ying-Jing& Tsai, Sheng-Hong& Lien, Pham Thi Kim…[et al.]. Evaluation of an Epitypified Ophiocordyceps formosana (Cordyceps s.l.) for Its Pharmacological Potential. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1061224
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061224