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Do Herbal Formulas Influence the International Normalized Ratio of Patients Taking Warfarin? A Retrospective Study
Joint Authors
Moon, Sang Kwan
Park, Jung-Mi
Ko, Chang-Nam
Cho, Seung-Yeon
Jung, Woo Sang
Lu, Hsu-Yuan
Park, Seong-Uk
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Warfarin is a common anticoagulant agent for cardiovascular diseases, and it is known to interact with several foods and drugs.
Several studies report an interaction between warfarin and herbal medicines; however, the influence of herbal medicines on the international normalized ratio (INR) is still controversial.
We investigated the influence of herbal formulas on INR of patients taking warfarin.
We searched electronic medical records of inpatients for INR results.
Then, we compared the changes in INR and any adverse events between the group taking herbal formulas and warfarin (herbal group) and another group taking warfarin only (nonherbal group).
Eighty-six patients were included; 45 patients were assigned to the herbal group and 41 patients to the nonherbal group.
The herbal group had taken the same dose of warfarin for a longer period.
The nonherbal group had a slightly higher mean INR value than the herbal group.
The ratio of INR less than 2 and greater than 3, the ratio of INR that increased or decreased by one or more compared to the initial INR, and the ratio of adverse events were not significantly different between the two groups.
It is suggested that use of herbal formulas may not influence INR value.
American Psychological Association (APA)
Lu, Hsu-Yuan& Cho, Seung-Yeon& Park, Seong-Uk& Jung, Woo Sang& Moon, Sang Kwan& Park, Jung-Mi…[et al.]. 2015. Do Herbal Formulas Influence the International Normalized Ratio of Patients Taking Warfarin? A Retrospective Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1061249
Modern Language Association (MLA)
Lu, Hsu-Yuan…[et al.]. Do Herbal Formulas Influence the International Normalized Ratio of Patients Taking Warfarin? A Retrospective Study. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1061249
American Medical Association (AMA)
Lu, Hsu-Yuan& Cho, Seung-Yeon& Park, Seong-Uk& Jung, Woo Sang& Moon, Sang Kwan& Park, Jung-Mi…[et al.]. Do Herbal Formulas Influence the International Normalized Ratio of Patients Taking Warfarin? A Retrospective Study. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1061249
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061249