Essential Oils from Ugandan Aromatic Medicinal Plants: Chemical Composition and Growth Inhibitory Effects on Oral Pathogens
Joint Authors
Gustafsson, A.
Ocheng, Francis
Bwanga, Freddie
Softrata, Abier
Azeem, Muhammad
Pütsep, Katrin
Borg-Karlson, Anna-Karin
Obua, Celestino
Joloba, Moses L.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-10
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The study assessed the growth inhibitory effects of essential oils extracted from ten Ugandan medicinal plants (Bidens pilosa, Helichrysum odoratissimum, Vernonia amygdalina, Hoslundia opposita, Ocimum gratissimum, Cymbopogon citratus, Cymbopogon nardus, Teclea nobilis, Zanthoxylum chalybeum, and Lantana trifolia) used traditionally in the management of oral diseases against oral pathogens.
Chemical compositions of the oils were explored by GC-MS.
Inhibitory effects of the oils were assessed on periodontopathic Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans and cariogenic Streptococcus mutans and Lactobacillus acidophilus using broth dilution methods at concentrations of 1%, 0.1%, and 0.01%.
The most sensitive organism was A.
actinomycetemcomitans.
Its growth was markedly inhibited by six of the oils at all the concentrations tested.
Essential oil from C.
nardus exhibited the highest activity with complete growth inhibition of A.
actinomycetemcomitans and P.
gingivalis at all the three concentrations tested, the major constituents in the oil being mainly oxygenated sesquiterpenes.
Most of the oils exhibited limited effects on L.
acidophilus.
We conclude that essential oils from the studied plants show marked growth inhibitory effects on periodontopathic A.
actinomycetemcomitans and P.
gingivalis, moderate effects on cariogenic S.
mutans, and the least effect on L.
acidophilus.
The present study constitutes a basis for further investigations and development of certain oils into alternative antiplaque agents.
American Psychological Association (APA)
Ocheng, Francis& Bwanga, Freddie& Joloba, Moses L.& Softrata, Abier& Azeem, Muhammad& Pütsep, Katrin…[et al.]. 2015. Essential Oils from Ugandan Aromatic Medicinal Plants: Chemical Composition and Growth Inhibitory Effects on Oral Pathogens. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1061259
Modern Language Association (MLA)
Ocheng, Francis…[et al.]. Essential Oils from Ugandan Aromatic Medicinal Plants: Chemical Composition and Growth Inhibitory Effects on Oral Pathogens. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1061259
American Medical Association (AMA)
Ocheng, Francis& Bwanga, Freddie& Joloba, Moses L.& Softrata, Abier& Azeem, Muhammad& Pütsep, Katrin…[et al.]. Essential Oils from Ugandan Aromatic Medicinal Plants: Chemical Composition and Growth Inhibitory Effects on Oral Pathogens. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1061259
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061259