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Chemical Composition and Vasorelaxant and Antispasmodic Effects of Essential Oil from Rosa indica L. Petals
Joint Authors
Rasheed, Hafiz Majid
Khan, Taous
Wahid, Fazli
Khan, Rasool
Shah, Abdul Jabbar
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-19
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Rosa indica L.
belongs to the family Rosaceae and is locally known as gulaab.
It has different traditional uses in cardiovascular and gastrointestinal disorders but there is no scientific data available in this regard.
Therefore, the basic aim of this study was to explore the chemical composition and gastrointestinal and cardiovascular effects of the essential oil obtained from R.
indica.
The chemical composition of the essential oil was investigated using gas chromatography-mass spectrometry (GC-MS) technique.
The cardiovascular and gastrointestinal effects were investigated using electrophysiological measurements.
The GC-MS analysis of the essential oil showed various chemical components including acetic acid, mercaptohexyl ester, butanoic acid, 2-methyl-5-oxo-1-cyclopentene-1-yl ester, artemiseole, methyl santonilate, isosteviol, caryophyllene oxide, pentyl phenyl acetate, dihydromyrcene, 1,5-octadecadien, octadecanoic acid, ethyl ester, palmitic acid (2-phenyl-1,3-dioxolan-4-yl methyl ester), santolina epoxide, and 9-farnesene.
The electrophysiological measurements revealed that essential oil was more potent against K+ (80 mM) than phenylephrine precontractions using isolated rabbit aorta preparations.
In isolated rabbit jejunum preparations, it showed more potency against high K+ induced contractions than spontaneous contractions.
Considering these evidences, it can be concluded that R.
indica essential oil may work as a complementary and alternative medicine in gastrointestinal and cardiovascular diseases.
American Psychological Association (APA)
Rasheed, Hafiz Majid& Khan, Taous& Wahid, Fazli& Khan, Rasool& Shah, Abdul Jabbar. 2015. Chemical Composition and Vasorelaxant and Antispasmodic Effects of Essential Oil from Rosa indica L. Petals. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1061311
Modern Language Association (MLA)
Rasheed, Hafiz Majid…[et al.]. Chemical Composition and Vasorelaxant and Antispasmodic Effects of Essential Oil from Rosa indica L. Petals. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1061311
American Medical Association (AMA)
Rasheed, Hafiz Majid& Khan, Taous& Wahid, Fazli& Khan, Rasool& Shah, Abdul Jabbar. Chemical Composition and Vasorelaxant and Antispasmodic Effects of Essential Oil from Rosa indica L. Petals. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1061311
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061311