Bacoside A: Role in Cigarette Smoking Induced Changes in Brain
Joint Authors
Vani, G.
Anbarasi, K.
Shyamaladevi, C. S.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-27
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Cigarette smoking (CS) is a major health hazard that exerts diverse physiologic and biochemical effects mediated by the components present and generated during smoking.
Recent experimental studies have shown predisposition to several biological consequences from both active and passive cigarette smoke exposure.
In particular, passive smoking is linked to a number of adverse health effects which are equally harmful as active smoking.
A pragmatic approach should be considered for designing a pharmacological intervention to combat the adverse effects of passive smoking.
This review describes the results from a controlled experimental condition, testing the effect of bacoside A (BA) on the causal role of passive/secondhand smoke exposure that caused pathological and neurological changes in rat brain.
Chronic exposure to cigarette smoke induced significant changes in rat brain histologically and at the neurotransmitter level, lipid peroxidation states, mitochondrial functions, membrane alterations, and apoptotic damage in rat brain.
Bacoside A is a neuroactive agent isolated from Bacopa monnieri.
As a neuroactive agent, BA was effective in combating these changes.
Future research should examine the effects of BA at molecular level and assess its functional effects on neurobiological and behavioral processes associated with passive smoke.
American Psychological Association (APA)
Vani, G.& Anbarasi, K.& Shyamaladevi, C. S.. 2015. Bacoside A: Role in Cigarette Smoking Induced Changes in Brain. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1061316
Modern Language Association (MLA)
Vani, G.…[et al.]. Bacoside A: Role in Cigarette Smoking Induced Changes in Brain. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-16.
https://search.emarefa.net/detail/BIM-1061316
American Medical Association (AMA)
Vani, G.& Anbarasi, K.& Shyamaladevi, C. S.. Bacoside A: Role in Cigarette Smoking Induced Changes in Brain. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1061316
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061316