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Propolis Is an Efficient Fungicide and Inhibitor of Biofilm Production by Vaginal Candida albicans
Joint Authors
Consolaro, Marcia Edilaine Lopes
Bruschi, Marcos Luciano
Capoci, Isis Regina Grenier
Bonfim-Mendonça, Patrícia de Souza
Arita, Glaucia Sayuri
Pereira, Raphaela Regina de Araújo
Negri, Melyssa
Svidzinski, Terezinha Inez Estivalet
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-01
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Vulvovaginal candidiasis (VVC) is one of the most common genital infections in women.
The therapeutic arsenal remains restricted, and some alternatives to VVC treatment are being studied.
The present study evaluated the influence of a propolis extractive solution (PES) on biofilm production by Candida albicans isolated from patients with VVC.
Susceptibility testing was used to verify the minimum inhibitory concentration (MIC) of PES, with fluconazole and nystatin as controls.
The biofilm formation of 29 vaginal isolates of C.
albicans and a reference strain that were exposed to PES was evaluated using crystal violet staining.
Colony-forming units were evaluated, proteins and carbohydrates of the matrix biofilm were quantified, and scanning electron microscopy was performed.
The MIC of PES ranged from 68.35 to 546.87 μg/mL of total phenol content in gallic acid.
A concentration of 546.87 μg/mL was able to cause the death of 75.8% of the isolates.
PES inhibited biofilm formation by C.
albicans from VVC.
Besides antifungal activity, PES appears to present important antibiofilm activity on abiotic surfaces, indicating that it may have an additional beneficial effect in the treatment of VVC.
American Psychological Association (APA)
Capoci, Isis Regina Grenier& Bonfim-Mendonça, Patrícia de Souza& Arita, Glaucia Sayuri& Pereira, Raphaela Regina de Araújo& Consolaro, Marcia Edilaine Lopes& Bruschi, Marcos Luciano…[et al.]. 2015. Propolis Is an Efficient Fungicide and Inhibitor of Biofilm Production by Vaginal Candida albicans. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1061319
Modern Language Association (MLA)
Capoci, Isis Regina Grenier…[et al.]. Propolis Is an Efficient Fungicide and Inhibitor of Biofilm Production by Vaginal Candida albicans. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1061319
American Medical Association (AMA)
Capoci, Isis Regina Grenier& Bonfim-Mendonça, Patrícia de Souza& Arita, Glaucia Sayuri& Pereira, Raphaela Regina de Araújo& Consolaro, Marcia Edilaine Lopes& Bruschi, Marcos Luciano…[et al.]. Propolis Is an Efficient Fungicide and Inhibitor of Biofilm Production by Vaginal Candida albicans. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1061319
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061319