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Antimicrobial, Antioxidant, Anti-Inflammatory, and Cytotoxic Activities of Propolis from the Stingless Bee Tetragonisca fiebrigi (Jataí)
Joint Authors
Cardoso, Claudia Andrea Lima
Damião, Marcio José
Campos, Jaqueline Ferreira
Santos, Uilson Pereira dos
Rocha, Paola dos Santos da
Balestieri, José Benedito Perrella
de Picoli Souza, Kely
Santos, Edson Lucas dos
Miranda Fernandes Estevinho, M. L.
Paredes-Gamero, Edgar J.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-22
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Propolis from stingless bees Tetragonisca fiebrigi found in Brazil is used in folk medicine by their nutritional and therapeutic properties.
However, there are no scientific records evidencing such properties.
The present study was designed to investigate the chemical composition and the biological properties of propolis from T.
fiebrigi.
For this, the chemical composition of the ethanol extract of propolis (EEP) was determined by GC-MS and presented phenolic compounds, alcohol, and terpenes as its major class compounds.
The antimicrobial activity was accessed in gram-positive and gram-negative bacteria and in fungi, isolated from different biological fluids and reference strains.
The EEP was active against all microorganisms and showed antioxidant activity by scavenging free radicals, inhibiting hemolysis and lipid peroxidation in human erythrocytes incubated with an oxidizing agent.
The anti-inflammatory potential of the EEP was confirmed by inhibition of the hyaluronidase enzyme.
The cytotoxic activity was concentration-dependent against K562 cells, with a predominance of death by necrosis.
Taken together, these results show that propolis from T.
fiebrigi has important therapeutic activities, which suggest its potential application in the pharmaceutical industry, as well as in health foods, beverages, and nutritional supplements.
American Psychological Association (APA)
Campos, Jaqueline Ferreira& Santos, Uilson Pereira dos& Rocha, Paola dos Santos da& Damião, Marcio José& Balestieri, José Benedito Perrella& Cardoso, Claudia Andrea Lima…[et al.]. 2015. Antimicrobial, Antioxidant, Anti-Inflammatory, and Cytotoxic Activities of Propolis from the Stingless Bee Tetragonisca fiebrigi (Jataí). Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1061326
Modern Language Association (MLA)
Campos, Jaqueline Ferreira…[et al.]. Antimicrobial, Antioxidant, Anti-Inflammatory, and Cytotoxic Activities of Propolis from the Stingless Bee Tetragonisca fiebrigi (Jataí). Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1061326
American Medical Association (AMA)
Campos, Jaqueline Ferreira& Santos, Uilson Pereira dos& Rocha, Paola dos Santos da& Damião, Marcio José& Balestieri, José Benedito Perrella& Cardoso, Claudia Andrea Lima…[et al.]. Antimicrobial, Antioxidant, Anti-Inflammatory, and Cytotoxic Activities of Propolis from the Stingless Bee Tetragonisca fiebrigi (Jataí). Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1061326
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061326