Neuropharmacological Potential of Gastrodia elata Blume and Its Components
Joint Authors
Jang, Jung-Hee
Son, Yeonghoon
Kang, Seong Soo
Bae, Chun-Sik
Kim, Jong-Choon
Kim, Sung-Ho
Shin, Taekyun
Moon, Changjong
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-12
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Research has been conducted in various fields in an attempt to develop new therapeutic agents for incurable neurodegenerative diseases.
Gastrodia elata Blume (GE), a traditional herbal medicine, has been used in neurological disorders as an anticonvulsant, analgesic, and sedative medication.
Several neurodegenerative models are characterized by oxidative stress and inflammation in the brain, which lead to cell death via multiple extracellular and intracellular signaling pathways.
The blockade of certain signaling cascades may represent a compensatory therapy for injured brain tissue.
Antioxidative and anti-inflammatory compounds isolated from natural resources have been investigated, as have various synthetic chemicals.
Specifically, GE rhizome extract and its components have been shown to protect neuronal cells and recover brain function in various preclinical brain injury models by inhibiting oxidative stress and inflammatory responses.
The present review discusses the neuroprotective potential of GE and its components and the related mechanisms; we also provide possible preventive and therapeutic strategies for neurodegenerative disorders using herbal resources.
American Psychological Association (APA)
Jang, Jung-Hee& Son, Yeonghoon& Kang, Seong Soo& Bae, Chun-Sik& Kim, Jong-Choon& Kim, Sung-Ho…[et al.]. 2015. Neuropharmacological Potential of Gastrodia elata Blume and Its Components. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1061338
Modern Language Association (MLA)
Jang, Jung-Hee…[et al.]. Neuropharmacological Potential of Gastrodia elata Blume and Its Components. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-14.
https://search.emarefa.net/detail/BIM-1061338
American Medical Association (AMA)
Jang, Jung-Hee& Son, Yeonghoon& Kang, Seong Soo& Bae, Chun-Sik& Kim, Jong-Choon& Kim, Sung-Ho…[et al.]. Neuropharmacological Potential of Gastrodia elata Blume and Its Components. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1061338
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061338