Chilean Strawberry Consumption Protects against LPS-Induced Liver Injury by Anti-Inflammatory and Antioxidant Capability in Sprague-Dawley Rats
Joint Authors
Molinett, Sebastian
Nuñez, Francisca
Moya-León, María Alejandra
Zúñiga-Hernández, Jessica
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-17
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The Chilean strawberry fruit has high content of antioxidants and polyphenols.
Previous studies evidenced antioxidant properties by in vitro methods.
However, the antioxidant effect and its impact as functional food on animal health have not been evaluated.
In this study, rats were fed with a Chilean strawberry aqueous extract (4 g/kg of animal per day) and then subjected to LPS-induced liver injury (5 mg/kg).
Transaminases and histological studies revealed a reduction in liver injury in rats fed with strawberry aqueous extract compared with the control group.
Additionally, white strawberry supplementation significantly reduced the serum levels and gene expression of TNF-α, IL-6, and IL-1β cytokines compared with nonsupplemented rats.
The level of F2-isoprostanes and GSH/GSSG indicated a reduction in liver oxidative stress by the consumption of strawberry aqueous extract.
Altogether, the evidence suggests that dietary supplementation of rats with a Chilean white strawberry aqueous extract favours the normalization of oxidative and inflammatory responses after a liver injury induced by LPS.
American Psychological Association (APA)
Molinett, Sebastian& Nuñez, Francisca& Moya-León, María Alejandra& Zúñiga-Hernández, Jessica. 2015. Chilean Strawberry Consumption Protects against LPS-Induced Liver Injury by Anti-Inflammatory and Antioxidant Capability in Sprague-Dawley Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1061351
Modern Language Association (MLA)
Molinett, Sebastian…[et al.]. Chilean Strawberry Consumption Protects against LPS-Induced Liver Injury by Anti-Inflammatory and Antioxidant Capability in Sprague-Dawley Rats. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1061351
American Medical Association (AMA)
Molinett, Sebastian& Nuñez, Francisca& Moya-León, María Alejandra& Zúñiga-Hernández, Jessica. Chilean Strawberry Consumption Protects against LPS-Induced Liver Injury by Anti-Inflammatory and Antioxidant Capability in Sprague-Dawley Rats. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1061351
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061351