The Expression Patterns of c-Fos and c-Jun Induced by Different Frequencies of Electroacupuncture in the Brain
Joint Authors
Ding, Yi
Cui, Lu-ying
Ding, Ming-Xing
Qiu, Zheng-Ying
Hu, Man-Li
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-29
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
To investigate patterns of c-Fos and c-Jun expression induced by different frequencies of electroacupuncture (EA) in the brain, goats were stimulated by EA of 0, 2, 60, or 100 Hz at a set of “Baihui, Santai, Ergen, and Sanyangluo” points for 30 min.
The pain threshold was measured using the potassium iontophoresis method.
The levels of c-Fos and c-Jun were determined with Streptavidin-Biotin Complex immunohistochemistry.
The results showed that the pain threshold induced by 60 Hz was 82.2% higher ( P < 0.01 ) than that by 0, 2, or 100 Hz (6.5%, 35.2%, or 40.9%).
EA induced increased c-Fos and c-Jun expression in most analgesia-related nuclei and areas in the brain.
Sixty Hz EA increased more c-Fos or c-Jun expression than 2 Hz or 100 Hz EA in all the measured nuclei and areas except for the nucleus accumbens, the area septalis lateralis, the caudate nucleus, the nucleus amygdala basalis, and the locus coeruleus, in which c-Fos or c-Jun expressions induced by 60 Hz EA did not differ from those by 2 Hz or 100 Hz EA.
It was suggested that 60 Hz EA activated more extensive neural circuits in goats, which may contribute to optimal analgesic effects.
American Psychological Association (APA)
Qiu, Zheng-Ying& Ding, Yi& Cui, Lu-ying& Hu, Man-Li& Ding, Ming-Xing. 2015. The Expression Patterns of c-Fos and c-Jun Induced by Different Frequencies of Electroacupuncture in the Brain. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1061369
Modern Language Association (MLA)
Qiu, Zheng-Ying…[et al.]. The Expression Patterns of c-Fos and c-Jun Induced by Different Frequencies of Electroacupuncture in the Brain. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1061369
American Medical Association (AMA)
Qiu, Zheng-Ying& Ding, Yi& Cui, Lu-ying& Hu, Man-Li& Ding, Ming-Xing. The Expression Patterns of c-Fos and c-Jun Induced by Different Frequencies of Electroacupuncture in the Brain. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1061369
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061369