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Safety of Chinese Herbal Medicine for Chronic Obstructive Pulmonary Disease
Joint Authors
Zhang, Anthony Lin
Lu, Chuanjian
Wu, Lei
Liu, Shaonan
Shergis, Johannah
Coyle, Meaghan
Xue, Charlie Changli
Guo, Xinfeng
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-26
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Chinese herbal medicine (CHM) is increasingly used by patients with chronic obstructive pulmonary disease (COPD); however, there has been no systematic evaluation of its safety.
This review examined the adverse events (AEs) reported in clinical studies of CHM for COPD.
Five English databases (PubMed, Embase, CINAHL, AMED, and CENTRAL) and four Chinese databases (CBM, CNKI, CQVIP, and Wanfang Data) were searched from inception to May 2013.
Adverse event data, including nature, severity, author-assigned causality, management, and outcome, were extracted from included studies.
Descriptive statistics were used for the rate of adverse events.
Of the 152 included studies, AEs were reported in 47 studies.
The rate of adverse events was slightly lower in the CHM groups compared with controls (84 events in 5,909 participants, 1.4% versus 102 events in 5,676 participants, 1.8%).
The most frequently reported adverse event was nausea (28 cases in the CHM groups and 19 cases in the control groups), which was more common in studies where CHM was combined with pharmacotherapy to treat acute exacerbation of COPD.
Other frequent adverse events were abdominal discomfort, dry mouth, and dizziness.
Detailed information about the adverse events was scant.
Overall, CHM appears to be well tolerated in people with COPD.
American Psychological Association (APA)
Coyle, Meaghan& Shergis, Johannah& Liu, Shaonan& Wu, Lei& Zhang, Anthony Lin& Guo, Xinfeng…[et al.]. 2015. Safety of Chinese Herbal Medicine for Chronic Obstructive Pulmonary Disease. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1061431
Modern Language Association (MLA)
Coyle, Meaghan…[et al.]. Safety of Chinese Herbal Medicine for Chronic Obstructive Pulmonary Disease. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1061431
American Medical Association (AMA)
Coyle, Meaghan& Shergis, Johannah& Liu, Shaonan& Wu, Lei& Zhang, Anthony Lin& Guo, Xinfeng…[et al.]. Safety of Chinese Herbal Medicine for Chronic Obstructive Pulmonary Disease. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1061431
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061431