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Eight Weeks of Cosmos caudatus (Ulam Raja) Supplementation Improves Glycemic Status in Patients with Type 2 Diabetes: A Randomized Controlled Trial
Joint Authors
Cheng, Shi-Hui
Ismail, Amin
Anthony, Joseph
Ng, Ooi Chuan
Hamid, Azizah Abdul
Barakatun-Nisak, Mohd Yusof
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-06
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objectives.
Optimizing glycemic control is crucial to prevent type 2 diabetes related complications.
Cosmos caudatus is reported to have promising effect in improving plasma blood glucose in an animal model.
However, its impact on human remains ambiguous.
This study was carried out to evaluate the effectiveness of C.
caudatus on glycemic status in patients with type 2 diabetes.
Materials and Methods.
In this randomized controlled trial with two-arm parallel-group design, a total of 101 subjects with type 2 diabetes were randomly allocated to diabetic-ulam or diabetic controls for eight weeks.
Subjects in diabetic-ulam group consumed 15 g of C.
caudatus daily for eight weeks while diabetic controls abstained from taking C.
caudatus.
Both groups received the standard lifestyle advice.
Results.
After 8 weeks of supplementation, C.
caudatus significantly reduced serum insulin (−1.16 versus +3.91), reduced HOMA-IR (−1.09 versus +1.34), and increased QUICKI (+0.05 versus −0.03) in diabetic-ulam group compared with the diabetic controls.
HbA1C level was improved although it is not statistically significant (−0.76% versus −0.37%).
C.
caudatus was safe to consume.
Conclusions.
C.
caudatus supplementation significantly improves insulin resistance and insulin sensitivity in patients with type 2 diabetes.
American Psychological Association (APA)
Cheng, Shi-Hui& Ismail, Amin& Anthony, Joseph& Ng, Ooi Chuan& Hamid, Azizah Abdul& Barakatun-Nisak, Mohd Yusof. 2015. Eight Weeks of Cosmos caudatus (Ulam Raja) Supplementation Improves Glycemic Status in Patients with Type 2 Diabetes: A Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1061467
Modern Language Association (MLA)
Cheng, Shi-Hui…[et al.]. Eight Weeks of Cosmos caudatus (Ulam Raja) Supplementation Improves Glycemic Status in Patients with Type 2 Diabetes: A Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1061467
American Medical Association (AMA)
Cheng, Shi-Hui& Ismail, Amin& Anthony, Joseph& Ng, Ooi Chuan& Hamid, Azizah Abdul& Barakatun-Nisak, Mohd Yusof. Eight Weeks of Cosmos caudatus (Ulam Raja) Supplementation Improves Glycemic Status in Patients with Type 2 Diabetes: A Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1061467
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061467