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The Value of Safflower Yellow Injection for the Treatment of Acute Cerebral Infarction: A Randomized Controlled Trial
Joint Authors
Li, Le-Jun
Li, Yu-Mei
Qiao, Ben-Yu
Jiang, Shan
Li, Xin
Du, Hong-Ming
Han, Peng-Cheng
Shi, Jiong
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-17
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Safflower Yellow Injection has been reported as a treatment for acute cerebral infarction in recent studies in China.
However, there is a lack of availability of the evidence for the efficacy and safety of Safflower Yellow Injection for the treatment of acute ischemic stroke.
So we investigated the effects of Safflower Yellow Injection for the treatment of acute cerebral infarction.
Method.
All subjects were randomly divided into Safflower Yellow Injection group given Safflower Yellow Injection (80 mg) and control group given placebo (0 mg) injection by intravenous drop once daily for 14 days.
National Institute of Health Stroke Scale (NIHSS); hemorheological detection; coagulation function; and serum inflammatory markers, tumor necrosis factor-alpha (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6), were used to investigate the effects before and 14 days after the treatment.
Results.
The scores of NIHSS were decreased on day 7 and day 14 after treatment.
The hemorheological index of RBC deformation and RBC aggregation were significantly improved, prothrombin time (PT) increased, and fibrinogen (FIB) and TNF-α, IL-1β, and IL-6 were decreased in patients treated with Safflower Yellow injection on day 14 after treatment (P<0.05).
Conclusion.
Data suggests that Safflower Yellow Injection therapy may be beneficial for acute cerebral infarction.
American Psychological Association (APA)
Li, Le-Jun& Li, Yu-Mei& Qiao, Ben-Yu& Jiang, Shan& Li, Xin& Du, Hong-Ming…[et al.]. 2015. The Value of Safflower Yellow Injection for the Treatment of Acute Cerebral Infarction: A Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1061549
Modern Language Association (MLA)
Li, Le-Jun…[et al.]. The Value of Safflower Yellow Injection for the Treatment of Acute Cerebral Infarction: A Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1061549
American Medical Association (AMA)
Li, Le-Jun& Li, Yu-Mei& Qiao, Ben-Yu& Jiang, Shan& Li, Xin& Du, Hong-Ming…[et al.]. The Value of Safflower Yellow Injection for the Treatment of Acute Cerebral Infarction: A Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1061549
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1061549