In Vivo Antioxidant and Hypolipidemic Effects of Fermented Mung Bean on Hypercholesterolemic Mice
Joint Authors
Beh, Boon Kee
Jaganath, InduBala
Mohd Ali, Norlaily
Alitheen, Noorjahan Banu
Koh, Soo Peng
Mohamad, Nurul Elyani
Long, Kamariah
Ho, Wan Yong
Yeap, Swee Keong
Mohd Yusof, Hamidah
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-17
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Legumes have previously been reported with hypolipidemic effect caused by the presence of flavonoid.
This study was carried out to evaluate the antioxidant and hypolipidemic effects of fermented mung bean on hypercholesterolemic mice.
Blood from all mice was collected and subjected to serum lipid and liver profiles biochemical analysis and quantitative RT-PCR for atherosclerosis related gene expressions.
Besides, livers were collected for antioxidant assays and histopathology evaluation.
Fermented mung bean was found to reduce the level of serum lipid and liver enzyme profiles of hypercholesterolemic mice.
Furthermore, liver antioxidant and nitric oxide levels were also significantly restored by fermented mung bean in a dosage dependent manner.
The gene expression study indicated that Apoe and Bcl2a1a were upregulated while Npy and Vwf expressions were downregulated after the treatment.
The effects of fermented mung bean were greater than nonfermented mung bean.
These results indicated that fermented mung bean possessed antioxidants that lead to its hypolipidemic effect on hypercholesterolemic mice.
American Psychological Association (APA)
Yeap, Swee Keong& Beh, Boon Kee& Ho, Wan Yong& Mohd Yusof, Hamidah& Mohamad, Nurul Elyani& Mohd Ali, Norlaily…[et al.]. 2015. In Vivo Antioxidant and Hypolipidemic Effects of Fermented Mung Bean on Hypercholesterolemic Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1062398
Modern Language Association (MLA)
Yeap, Swee Keong…[et al.]. In Vivo Antioxidant and Hypolipidemic Effects of Fermented Mung Bean on Hypercholesterolemic Mice. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1062398
American Medical Association (AMA)
Yeap, Swee Keong& Beh, Boon Kee& Ho, Wan Yong& Mohd Yusof, Hamidah& Mohamad, Nurul Elyani& Mohd Ali, Norlaily…[et al.]. In Vivo Antioxidant and Hypolipidemic Effects of Fermented Mung Bean on Hypercholesterolemic Mice. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1062398
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1062398