In Vivo Antioxidant and Hypolipidemic Effects of Fermented Mung Bean on Hypercholesterolemic Mice

Joint Authors

Beh, Boon Kee
Jaganath, InduBala
Mohd Ali, Norlaily
Alitheen, Noorjahan Banu
Koh, Soo Peng
Mohamad, Nurul Elyani
Long, Kamariah
Ho, Wan Yong
Yeap, Swee Keong
Mohd Yusof, Hamidah

Source

Evidence-Based Complementary and Alternative Medicine

Issue

Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2015-05-17

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Medicine

Abstract EN

Legumes have previously been reported with hypolipidemic effect caused by the presence of flavonoid.

This study was carried out to evaluate the antioxidant and hypolipidemic effects of fermented mung bean on hypercholesterolemic mice.

Blood from all mice was collected and subjected to serum lipid and liver profiles biochemical analysis and quantitative RT-PCR for atherosclerosis related gene expressions.

Besides, livers were collected for antioxidant assays and histopathology evaluation.

Fermented mung bean was found to reduce the level of serum lipid and liver enzyme profiles of hypercholesterolemic mice.

Furthermore, liver antioxidant and nitric oxide levels were also significantly restored by fermented mung bean in a dosage dependent manner.

The gene expression study indicated that Apoe and Bcl2a1a were upregulated while Npy and Vwf expressions were downregulated after the treatment.

The effects of fermented mung bean were greater than nonfermented mung bean.

These results indicated that fermented mung bean possessed antioxidants that lead to its hypolipidemic effect on hypercholesterolemic mice.

American Psychological Association (APA)

Yeap, Swee Keong& Beh, Boon Kee& Ho, Wan Yong& Mohd Yusof, Hamidah& Mohamad, Nurul Elyani& Mohd Ali, Norlaily…[et al.]. 2015. In Vivo Antioxidant and Hypolipidemic Effects of Fermented Mung Bean on Hypercholesterolemic Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1062398

Modern Language Association (MLA)

Yeap, Swee Keong…[et al.]. In Vivo Antioxidant and Hypolipidemic Effects of Fermented Mung Bean on Hypercholesterolemic Mice. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1062398

American Medical Association (AMA)

Yeap, Swee Keong& Beh, Boon Kee& Ho, Wan Yong& Mohd Yusof, Hamidah& Mohamad, Nurul Elyani& Mohd Ali, Norlaily…[et al.]. In Vivo Antioxidant and Hypolipidemic Effects of Fermented Mung Bean on Hypercholesterolemic Mice. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1062398

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1062398