Thread Embedding Acupuncture Inhibits Ultraviolet B Irradiation-Induced Skin Photoaging in Hairless Mice
Joint Authors
Choi, Byung Tae
Kim, Ha-Neui
Kim, Yoon-Jung
Shin, Mi-Sook
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-22
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Thread embedding acupuncture (TEA) is an acupuncture treatment applied to many diseases in Korean medical clinics because of its therapeutic effects by continuous stimulation to tissues.
It has recently been used to enhance facial skin appearance and antiaging, but data from evidence-based medicine are limited.
To investigate whether TEA therapy can inhibit skin photoaging by ultraviolet B (UVB) irradiation, we performed analyses for histology, histopathology, in situ zymography and western blot analysis in HR-1 hairless mice.
TEA treatment resulted in decreased wrinkle formation and skin thickness (Epidermis; P = 0.001 versus UV) in UVB irradiated mice and also inhibited degradation of collagen fibers ( P = 0.010 versus normal) by inhibiting proteolytic activity of gelatinase matrix-metalloproteinase-9 (MMP-9).
Western blot data showed that activation of c-Jun N-terminal kinase (JNK) induced by UVB ( P = 0.002 versus normal group) was significantly inhibited by TEA treatment ( P = 0.005 versus UV) with subsequent alleviation of MMP-9 activation ( P = 0.048 versus UV).
These results suggest that TEA treatment can have anti-photoaging effects on UVB-induced skin damage by maintenance of collagen density through regulation of expression of MMP-9 and related JNK signaling.
Therefore, TEA therapy may have potential roles as an alternative treatment for protection against skin damage from aging.
American Psychological Association (APA)
Kim, Yoon-Jung& Kim, Ha-Neui& Shin, Mi-Sook& Choi, Byung Tae. 2015. Thread Embedding Acupuncture Inhibits Ultraviolet B Irradiation-Induced Skin Photoaging in Hairless Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1062490
Modern Language Association (MLA)
Kim, Yoon-Jung…[et al.]. Thread Embedding Acupuncture Inhibits Ultraviolet B Irradiation-Induced Skin Photoaging in Hairless Mice. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1062490
American Medical Association (AMA)
Kim, Yoon-Jung& Kim, Ha-Neui& Shin, Mi-Sook& Choi, Byung Tae. Thread Embedding Acupuncture Inhibits Ultraviolet B Irradiation-Induced Skin Photoaging in Hairless Mice. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1062490
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1062490