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Traditional Chinese Medicine Decreases the Stroke Risk of Systemic Corticosteroid Treatment in Dermatitis: A Nationwide Population-Based Study
Joint Authors
Chen, Huey-Yi
Chen, Wen-Chi
Tsai, Kao-Sung
Yen, Chia-Sung
Wu, Po-Yuan
Chiang, Jen-Huai
Yang, Chung-Hsien
Shen, Jui-Lung
Chen, Yung-Hsiang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-05
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Epidemiological studies have shown a strong association between dermatitis and stroke.
Systemic corticosteroid, the mainstay treatment for dermatitis, could enhance the atherosclerotic process.
Traditional Chinese Medicine (TCM) has been used for dermatitis to decrease the side effects of corticosteroid.
However, the different stroke risk in dermatitis patients treated with systemic corticosteroid or TCM remains unclear.
This study identified 235,220 dermatitis patients and same comorbidity matched subjects between 2000 and 2009 from database of NHRI in Taiwan.
The two cohorts were followed until December 31, 2011.
The primary outcome of interest was new diagnosis of stroke.
The crude hazard ratio (HR) for future stroke among dermatitis patients treated with systemic corticosteroid was 1.40 (95% CI, 1.34–1.45; P<0.0001) and TCM was 1.09 (95% CI, 1.05–1.13; P<0.0001).
The log-rank test showed a higher cumulative incidence of ischemic stroke in the patient treated with only systemic corticosteroid group than that treated with systemic corticosteroid and TCM, only TCM, and neither systemic corticosteroid nor TCM in the matched cohort during the follow-up period (P<0.0001).
We demonstrated that patients treated with systemic corticosteroid had an increased risk of stroke and that the risk probably decreased by TCM treatment.
American Psychological Association (APA)
Tsai, Kao-Sung& Yen, Chia-Sung& Wu, Po-Yuan& Chiang, Jen-Huai& Shen, Jui-Lung& Yang, Chung-Hsien…[et al.]. 2015. Traditional Chinese Medicine Decreases the Stroke Risk of Systemic Corticosteroid Treatment in Dermatitis: A Nationwide Population-Based Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063325
Modern Language Association (MLA)
Tsai, Kao-Sung…[et al.]. Traditional Chinese Medicine Decreases the Stroke Risk of Systemic Corticosteroid Treatment in Dermatitis: A Nationwide Population-Based Study. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1063325
American Medical Association (AMA)
Tsai, Kao-Sung& Yen, Chia-Sung& Wu, Po-Yuan& Chiang, Jen-Huai& Shen, Jui-Lung& Yang, Chung-Hsien…[et al.]. Traditional Chinese Medicine Decreases the Stroke Risk of Systemic Corticosteroid Treatment in Dermatitis: A Nationwide Population-Based Study. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063325
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063325