Biothermodynamic Assay of Coptis-Evodia Herb Couples
Joint Authors
Yang, Hongbo
Su, Min
Yao, Qi
Zhao, Yanling
Chen, Danhong
Jia, Lei
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-30
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Objective.
To illustrate the difference in cold/hot natural properties and therapeutic effect of coptis-evodia herb couples by using cold/hot plate differentiating technology and microcalorimetry combined with material basis analysis in vivo and in vitro.
It showed that animal retention ratio in hot pad significantly decreased along with the decrease in coptis proportion in coptis-evodia herb couples.
In addition, Zuojin wan markedly reduced the retention ratio of gastritis mice in the hot pad, while Fanzuojin wan displayed an opposite result.
Further, Mg2+-ATPase, Ca2+-ATPase, and T-AOC activity significantly weakened in coptis-treated group in the livers of the mice.
In the gastric cells from the gastritis mice, Fanzuojin wan remarkably increased calorific value for growth and metabolism, while Zuojin wan significantly reduced the calorigenic effect.
It suggested that the changes in the major chemical compositions (especially alkaloids) were the material base-induced transformation between “cold” and “hot” syndromes.
The material basis which affected the transformation between “cold” and “hot” syndromes might be X2, X3, X4, X8, epiberberine hydrochloride, jatrorrhizine hydrochloride, coptisine sulphate, palmatine hydrochloride, and berberine hydrochloride.
The CHPD combined with microcalorimetry technology is a good method to determine the differences in the “cold” and “hot” natural properties of coptis-evodia herb couples.
American Psychological Association (APA)
Yang, Hongbo& Su, Min& Yao, Qi& Zhao, Yanling& Chen, Danhong& Jia, Lei. 2015. Biothermodynamic Assay of Coptis-Evodia Herb Couples. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1063334
Modern Language Association (MLA)
Yang, Hongbo…[et al.]. Biothermodynamic Assay of Coptis-Evodia Herb Couples. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1063334
American Medical Association (AMA)
Yang, Hongbo& Su, Min& Yao, Qi& Zhao, Yanling& Chen, Danhong& Jia, Lei. Biothermodynamic Assay of Coptis-Evodia Herb Couples. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1063334
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063334