Inhibitory Properties of Aqueous Ethanol Extracts of Propolis on Alpha-Glucosidase
Joint Authors
Zhang, Hongcheng
Wang, Guangxin
Beta, Trust
Dong, Jie
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-12
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The objective of the present study was to evaluate the inhibitory properties of various extracts of propolis on alpha-glucosidase from baker’s yeast and mammalian intestine.
Inhibitory activities of aqueous ethanol extracts of propolis were determined by using 4-nitrophenyl-D-glucopyranoside, sucrose and maltose as substrates, and acarbose as a positive reference.
All extracts were significantly effective in inhibiting α-glucosidase from baker’s yeast and rat intestinal sucrase in comparison with acarbose ( P < 0.05 ).
The 75% ethanol extracts of propolis (75% EEP) showed the highest inhibitory effect on α-glucosidase and sucrase and were a noncompetitive inhibition mode.
50% EEP, 95%, EEP and 100% EEP exhibited a mixed inhibition mode, while water extracts of propolis (WEP) and 25% EEP demonstrated a competitive inhibition mode.
Furthermore, WEP presented the highest inhibitory activity against maltase.
These results suggest that aqueous ethanol extracts of propolis may be used as nutraceuticals for the regulation of postprandial hyperglycemia.
American Psychological Association (APA)
Zhang, Hongcheng& Wang, Guangxin& Beta, Trust& Dong, Jie. 2015. Inhibitory Properties of Aqueous Ethanol Extracts of Propolis on Alpha-Glucosidase. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1063354
Modern Language Association (MLA)
Zhang, Hongcheng…[et al.]. Inhibitory Properties of Aqueous Ethanol Extracts of Propolis on Alpha-Glucosidase. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1063354
American Medical Association (AMA)
Zhang, Hongcheng& Wang, Guangxin& Beta, Trust& Dong, Jie. Inhibitory Properties of Aqueous Ethanol Extracts of Propolis on Alpha-Glucosidase. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1063354
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063354