Pharmacological Properties of Protocatechuic Acid and Its Potential Roles as Complementary Medicine
Joint Authors
Semaming, Yoswaris
Pannengpetch, Patchareewan
Chattipakorn, Siriporn C.
Chattipakorn, Nipon
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-09
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
This paper reviews the reported pharmacological properties of protocatechuic acid (PCA, 3,4-dihydroxy benzoic acid), a type of phenolic acid found in many food plants such as olives and white grapes.
PCA is a major metabolite of anthocyanin.
The pharmacological actions of PCA have been shown to include strong in vitro and in vivo antioxidant activity.
In in vivo experiments using rats and mice, PCA has been shown to exert anti-inflammatory as well as antihyperglycemic and antiapoptotic activities.
Furthermore, PCA has been shown to inhibit chemical carcinogenesis and exert proapoptotic and antiproliferative effects in different cancerous tissues.
Moreover, in vitro studies have shown PCA to have antimicrobial activities and also to exert synergistic interaction with some antibiotics against resistant pathogens.
This review aims to comprehensively summarize the pharmacological properties of PCA reported to date with an emphasis on its biological properties and mechanisms of action which could be therapeutically useful in a clinical setting.
American Psychological Association (APA)
Semaming, Yoswaris& Pannengpetch, Patchareewan& Chattipakorn, Siriporn C.& Chattipakorn, Nipon. 2015. Pharmacological Properties of Protocatechuic Acid and Its Potential Roles as Complementary Medicine. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1063361
Modern Language Association (MLA)
Semaming, Yoswaris…[et al.]. Pharmacological Properties of Protocatechuic Acid and Its Potential Roles as Complementary Medicine. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1063361
American Medical Association (AMA)
Semaming, Yoswaris& Pannengpetch, Patchareewan& Chattipakorn, Siriporn C.& Chattipakorn, Nipon. Pharmacological Properties of Protocatechuic Acid and Its Potential Roles as Complementary Medicine. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1063361
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063361