Chinese Herbal Decoction Based on Syndrome Differentiation as Maintenance Therapy in Patients with Extensive-Stage Small-Cell Lung Cancer: An Exploratory and Small Prospective Cohort Study
Joint Authors
Bao, Yanju
Liu, Rui
He, Shu lin
Zhao, Yuan chen
Zheng, Hong gang
Li, Cong huang
Qin, Ying gang
Hou, Wei
Hua, Bao Jin
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-01
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Objective.
To investigate the treatment effect and treatment length of Chinese herbal decoction (CHD) as maintenance therapy on patients with extensive-stage small-cell lung cancer (ES-SCLC) and to reflect the real syndrome differentiation (Bian Zheng) practices of traditional Chinese medicine (TCM).
Patients and Methods.
Different CHDs were prescribed for each patient based on syndrome differentiation.
The length of CHD treatment was divided into two phases for analyzing progression-free survival (PFS) and postprogression survival (PPS).
Results.
Three hundred and fifty-seven CHDs were prescribed based on syndrome differentiation during the study period.
Median PFS was significantly longer in patients who received CHD >3 months than patients who received CHD ≤3 months in the first phase (8.7 months versus 4.5 months; hazard ratio (HR), 0.52; 95% confidence interval (CI), 0.41–0.99; P=0.0009).
Median PPS was significantly longer in patients who received CHD >7 months than patients who received CHD ≤7 months in the second phase (11.7 months versus 5.1 months; HR, 2.32; 95% CI, 1.90–2.74; P=0.002).
Conclusion.
CHD could improve PFS and PPS, which are closely related to treatment time and deepness of response of first-line therapy.
In addition, CHD could improve body function and keep patients in a relatively stable state.
American Psychological Association (APA)
Liu, Rui& He, Shu lin& Zhao, Yuan chen& Zheng, Hong gang& Li, Cong huang& Bao, Yanju…[et al.]. 2015. Chinese Herbal Decoction Based on Syndrome Differentiation as Maintenance Therapy in Patients with Extensive-Stage Small-Cell Lung Cancer: An Exploratory and Small Prospective Cohort Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1063368
Modern Language Association (MLA)
Liu, Rui…[et al.]. Chinese Herbal Decoction Based on Syndrome Differentiation as Maintenance Therapy in Patients with Extensive-Stage Small-Cell Lung Cancer: An Exploratory and Small Prospective Cohort Study. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1063368
American Medical Association (AMA)
Liu, Rui& He, Shu lin& Zhao, Yuan chen& Zheng, Hong gang& Li, Cong huang& Bao, Yanju…[et al.]. Chinese Herbal Decoction Based on Syndrome Differentiation as Maintenance Therapy in Patients with Extensive-Stage Small-Cell Lung Cancer: An Exploratory and Small Prospective Cohort Study. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1063368
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063368