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Antimicrobial Activity of Oleanolic and Ursolic Acids: An Update
Joint Authors
Laurenti, Márcia Dalastra
Passero, Luiz Felipe Domingues
Lago, João Henrique G.
Jesus, Jéssica A.
Yamamoto, Eduardo S.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-22
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Triterpenoids are the most representative group of phytochemicals, as they comprise more than 20,000 recognized molecules.
These compounds are biosynthesized in plants via squalene cyclization, a C30 hydrocarbon that is considered to be the precursor of all steroids.
Due to their low hydrophilicity, triterpenes were considered to be inactive for a long period of time; however, evidence regarding their wide range of pharmacological activities is emerging, and elegant studies have highlighted these activities.
Several triterpenic skeletons have been described, including some that have presented with pentacyclic features, such as oleanolic and ursolic acids.
These compounds have displayed incontestable biological activity, such as antibacterial, antiviral, and antiprotozoal effects, which were not included in a single review until now.
Thus, the present review investigates the potential use of these triterpenes against human pathogens, including their mechanisms of action, via in vivo studies, and the future perspectives about the use of compounds for human or even animal health are also discussed.
American Psychological Association (APA)
Jesus, Jéssica A.& Lago, João Henrique G.& Laurenti, Márcia Dalastra& Yamamoto, Eduardo S.& Passero, Luiz Felipe Domingues. 2015. Antimicrobial Activity of Oleanolic and Ursolic Acids: An Update. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1063391
Modern Language Association (MLA)
Jesus, Jéssica A.…[et al.]. Antimicrobial Activity of Oleanolic and Ursolic Acids: An Update. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-14.
https://search.emarefa.net/detail/BIM-1063391
American Medical Association (AMA)
Jesus, Jéssica A.& Lago, João Henrique G.& Laurenti, Márcia Dalastra& Yamamoto, Eduardo S.& Passero, Luiz Felipe Domingues. Antimicrobial Activity of Oleanolic and Ursolic Acids: An Update. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1063391
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063391