Strong Manual Acupuncture Manipulation Could Better Inhibit Spike Frequency of the Dorsal Horn Neurons in Rats with Acute Visceral Nociception
Joint Authors
Hong, Shouhai
Ding, Shasha
Wu, Fei
Xi, Qiang
Li, Qiang
Zhou, Tao
Qing, Cai
Guo, Yongming
Guo, Yi
Liu, Yangyang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-15
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Afferent impulses from visceral nociception can be regulated by acupuncture at spinal cord level; however, the effects of different manual acupuncture (MA) manipulations on the afferent impulses are still unknown.
Here, we analyzed the spike frequency of excitatory gastric-related wide dynamic range (WDR) neurons in spinal dorsal horn (SDH) following acute gastric distension (GD) in rats and compared their responses to MA manipulations with four different frequencies (0.5, 1, 2, and 3 Hz) at Zusanli (ST36).
Results indicated that the spike frequency was increased by acute GD stimulation.
Under acute GD circumstances, the spike frequency was further activated by weak MA stimulation (0.5 and 1 Hz), while being significantly inhibited by strong MA stimulation (2 and 3 Hz).
After 10 minutes of the strong MA stimulation, same intensity of acute GD caused less spike frequency.
Our previous researches had demonstrated that different MA manipulations could increase spike frequency in an intensity-dependent manner in normal rats; these findings suggest that acupuncture may have different modulatory effects depending on the state of the stomach.
Since neuronal spike frequency was related to the level of nociception, the results suggest that strong MA manipulation may have better effect on acute visceral nociception.
American Psychological Association (APA)
Hong, Shouhai& Ding, Shasha& Wu, Fei& Xi, Qiang& Li, Qiang& Liu, Yangyang…[et al.]. 2015. Strong Manual Acupuncture Manipulation Could Better Inhibit Spike Frequency of the Dorsal Horn Neurons in Rats with Acute Visceral Nociception. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1063451
Modern Language Association (MLA)
Hong, Shouhai…[et al.]. Strong Manual Acupuncture Manipulation Could Better Inhibit Spike Frequency of the Dorsal Horn Neurons in Rats with Acute Visceral Nociception. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1063451
American Medical Association (AMA)
Hong, Shouhai& Ding, Shasha& Wu, Fei& Xi, Qiang& Li, Qiang& Liu, Yangyang…[et al.]. Strong Manual Acupuncture Manipulation Could Better Inhibit Spike Frequency of the Dorsal Horn Neurons in Rats with Acute Visceral Nociception. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1063451
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063451