Evaluation of Antibacterial and Antifungal Properties of Alchornea laxiflora (Benth.) Pax. & Hoffman
Joint Authors
Okoh, Anthony I.
Akinpelu, David A.
Abioye, Emmanuel O.
Aiyegoro, Olayinka A.
Akinpelu, Oluseun F.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-19
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Alchornea laxiflora leaf extract was tested against a range of microorganisms using standard microbiological methods for antimicrobial activities.
The extract inhibited the growth of all the bacterial and 15 fungal isolates tested.
The zones of inhibition exhibited against the test bacteria ranged between 12 mm and 24 mm and between 11 mm and 24 mm for the extract and the antibiotic streptomycin, respectively.
The zones of inhibition observed against the fungal isolates by the extract ranged between 12 mm and 23 mm.
The minimum inhibitory concentrations (MICs) and the minimum bactericidal concentrations (MBCs) exhibited by the extract against test bacteria ranged between 0.78 mg/mL–25 mg/mL and 1.56 mg/mL–25 mg/mL, respectively, while the MICs and minimum fungicidal concentrations (MFCs) values for the test fungi ranged between 8.75 mg/mL–35.00 mg/mL and 8.75 mg/mL–35.00 mg/L, respectively.
The preliminary phytochemical screening of the extract revealed the presence of alkaloids, tannins, flavonoids, saponins, and reducing sugars as major phytoconstituents in the extract.
A.
laxiflora leaf extract is a potent source of antibacterial and antifungal compounds; further studies on the extract are ongoing in our laboratories to elucidate the probable mechanism(s) of action on bacteria and fungi found to be susceptible to the extract.
American Psychological Association (APA)
Akinpelu, David A.& Abioye, Emmanuel O.& Aiyegoro, Olayinka A.& Akinpelu, Oluseun F.& Okoh, Anthony I.. 2015. Evaluation of Antibacterial and Antifungal Properties of Alchornea laxiflora (Benth.) Pax. & Hoffman. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063461
Modern Language Association (MLA)
Akinpelu, David A.…[et al.]. Evaluation of Antibacterial and Antifungal Properties of Alchornea laxiflora (Benth.) Pax. & Hoffman. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1063461
American Medical Association (AMA)
Akinpelu, David A.& Abioye, Emmanuel O.& Aiyegoro, Olayinka A.& Akinpelu, Oluseun F.& Okoh, Anthony I.. Evaluation of Antibacterial and Antifungal Properties of Alchornea laxiflora (Benth.) Pax. & Hoffman. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063461
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063461