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Intake of Novel Red Clover Supplementation for 12 Weeks Improves Bone Status in Healthy Menopausal Women
Joint Authors
Thorup, Anne Cathrine
Lambert, Max Norman
Kahr, Henriette Strøm
Bjerre, Mette
Jeppesen, Per Bendix
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-21
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Objective.
To investigate the effect by which daily consumption of a novel red clover (RC) extract influences bone health, inflammatory status, and cardiovascular health in healthy menopausal women.
Design.
A 12-week randomized, double-blinded, placebo-controlled trial involving 60 menopausal women receiving a daily dose of 150 mL RC extract containing 37.1 mg isoflavones (33.8 mg as aglycones) or placebo.
Methods.
Bone parameters were changes in bone mineral density (BMD), bone mineral content (BMC), and T-score at the lumbar spine and femoral neck.
Bone turnover (CTx) and inflammatory markers were measured in plasma and finally blood pressure (BP) was evaluated.
Results.
RC extract had positive effect on bone health, and only the women receiving the placebo experienced a decline in BMD (p<0.01) at the lumbar spine.
T-score at the lumbar spine only decreased in the placebo group (p<0.01).
CTx decreased in the RC group with −9.94 (±4.93)%, although not significant.
Conclusion.
Daily consumption of RC extract over a 12-week period was found to have a beneficial effect on bone health in menopausal women based on BMD and T-score at the lumbar spine and plasma CTx levels.
No changes in BP or inflammation markers were found and no side effects were observed.
American Psychological Association (APA)
Thorup, Anne Cathrine& Lambert, Max Norman& Kahr, Henriette Strøm& Bjerre, Mette& Jeppesen, Per Bendix. 2015. Intake of Novel Red Clover Supplementation for 12 Weeks Improves Bone Status in Healthy Menopausal Women. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1063467
Modern Language Association (MLA)
Thorup, Anne Cathrine…[et al.]. Intake of Novel Red Clover Supplementation for 12 Weeks Improves Bone Status in Healthy Menopausal Women. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1063467
American Medical Association (AMA)
Thorup, Anne Cathrine& Lambert, Max Norman& Kahr, Henriette Strøm& Bjerre, Mette& Jeppesen, Per Bendix. Intake of Novel Red Clover Supplementation for 12 Weeks Improves Bone Status in Healthy Menopausal Women. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1063467
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063467