Exploratory Clinical Trial to Evaluate the Efficacy of a Topical Traditional Chinese Herbal Medicine in Psoriasis Vulgaris
Joint Authors
Yan, Yuhe
Liu, Wali
Andres, Philippe
Pernin, Colette
Chantalat, Laurent
Briantais, Philippe
Lin, Albert
Feng, Lilian
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-05
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To evaluate the efficacy and safety of herbal ointment, Shi Du Ruan Gao, in patients with plaque-type psoriasis.
Design.
Single-center, randomized, investigator-blinded, parallel group, placebo-controlled study.
Participants.
One hundred outpatients with mild to moderate chronic plaque-type psoriasis were enrolled.
Intervention.
The patients applied either Shi Du Ruan Gao ointment or vehicle ointment topically to for 8 weeks.
Main Outcome Measures.
The outcomes were assessed using the following criteria: Total Severity Score (TSS, sum of erythema, scaling, and plaque elevation/induration, on a 0 to 4 scale), Investigator Global Assessment (IGA) evaluated on a 0 (Clear) to 4 (s to very severe) scale, and Global Subjects’ Assessment of treatment response on a 7-point scale from −1 (worse) to 5 (Cleared).
Results.
Significant reductions in the Total Severity Score (P<0.001) (mean score: 2.7 after Shi Du Ruan Gao treatment versus 5.1 in control subjects).
Both Investigator Global Assessment (IGA) and Global Subjects’ Assessment of treatment are better in the Shi Du Ruan Gao group than the control group (P<0.001).
Conclusion.
Shi Du Ruan Gao ointment was a safe, and effective therapy for plaque-type psoriasis.
American Psychological Association (APA)
Yan, Yuhe& Liu, Wali& Andres, Philippe& Pernin, Colette& Chantalat, Laurent& Briantais, Philippe…[et al.]. 2015. Exploratory Clinical Trial to Evaluate the Efficacy of a Topical Traditional Chinese Herbal Medicine in Psoriasis Vulgaris. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063495
Modern Language Association (MLA)
Yan, Yuhe…[et al.]. Exploratory Clinical Trial to Evaluate the Efficacy of a Topical Traditional Chinese Herbal Medicine in Psoriasis Vulgaris. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1063495
American Medical Association (AMA)
Yan, Yuhe& Liu, Wali& Andres, Philippe& Pernin, Colette& Chantalat, Laurent& Briantais, Philippe…[et al.]. Exploratory Clinical Trial to Evaluate the Efficacy of a Topical Traditional Chinese Herbal Medicine in Psoriasis Vulgaris. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063495
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063495