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Influence of the Alcohol Present in a Phytotherapic Tincture on Male Rat Lipid Profiles and Renal Function
Joint Authors
Silva, Fernanda Coleraus
de Souza, Juliete Gomes de Lara
Reichert, Alana Meira
Antonangelo, Renata Prestes
Suzuki, Rodrigo
Itinose, Ana Maria
Marek, Carla Brugin
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-28
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
This study evaluated the influence of the alcohol present in a formulation of the antiophidic phytotherapic tincture, Específico-Pessôa, on rat blood biochemical and hematological parameters, and on organ histology.
Three groups of rats were treated orally for 10, 15, or 30 days; one group received the tincture, the other received alcohol alone, and the third was a control group.
The results of this study indicated that cholesterol levels were significantly increased after 10 days in the alcohol and tincture groups, although these decreased after 30 days in the tincture group.
Triglyceride levels were significantly reduced after 15 days in the tincture group and after 30 days in the alcohol and tincture groups.
A higher creatinine level was observed in the alcohol and tincture groups after 15 and 30 days.
The uric acid levels in these groups were reduced at 10 and 30 days, although this metabolite was elevated at 15 days in the alcohol group.
Hydropic multifocal degeneration with lymphohistiocytic infiltration and some polymorphonuclear cells was observed in the livers of rats treated with either the tincture or alcohol.
These data demonstrate the importance of considering the potential actions of the alcohol present in pharmaceutical formulations.
American Psychological Association (APA)
Silva, Fernanda Coleraus& de Souza, Juliete Gomes de Lara& Reichert, Alana Meira& Antonangelo, Renata Prestes& Suzuki, Rodrigo& Itinose, Ana Maria…[et al.]. 2015. Influence of the Alcohol Present in a Phytotherapic Tincture on Male Rat Lipid Profiles and Renal Function. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1063575
Modern Language Association (MLA)
Silva, Fernanda Coleraus…[et al.]. Influence of the Alcohol Present in a Phytotherapic Tincture on Male Rat Lipid Profiles and Renal Function. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1063575
American Medical Association (AMA)
Silva, Fernanda Coleraus& de Souza, Juliete Gomes de Lara& Reichert, Alana Meira& Antonangelo, Renata Prestes& Suzuki, Rodrigo& Itinose, Ana Maria…[et al.]. Influence of the Alcohol Present in a Phytotherapic Tincture on Male Rat Lipid Profiles and Renal Function. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1063575
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063575