Hypoglycemic Effect of Ethanol and Ethyl Acetate Extract of Phellinus baumii Fruiting Body in Streptozotocin-Induced Diabetic Mice
Joint Authors
Wang, Wen-Han
Wu, Fei-Hua
Yang, Yan
Wu, Na
Zhang, Jing-Song
Feng, Na
Tang, Chuan-Hong
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-28
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We investigated hypoglycemic effect of ethanol (EtOH) and ethyl acetate extract acetate (AcOEt) extracts in streptozotocin- (STZ-) induced diabetic mice.
Our data showed the maximum inhibitory effect on the fasting plasma glucose (FPG) level was detected in STZ-induced diabetic mice administered with 400 mg/kg AcOEt extract of P.
baumii.
A lower glycated albumin (GA) level and a higher insulin level were observed in 400 mg/kg AcOEt and EtOH extract groups.
Moreover, 400 mg/kg AcOEt and EtOH extract exhibited a stronger effect on increasing size and cell number of islets.
The insulin expression level of β-cells and integrated optical density (IOD) value were significantly increased by the administration of 400 mg/kg AcOEt and EtOH extracts.
Taken together, AcOEt and EtOH extracts of P.
baumii fruiting body exhibited considerable hypoglycemic effect on STZ-induced diabetic mice.
American Psychological Association (APA)
Wang, Wen-Han& Wu, Fei-Hua& Yang, Yan& Wu, Na& Zhang, Jing-Song& Feng, Na…[et al.]. 2015. Hypoglycemic Effect of Ethanol and Ethyl Acetate Extract of Phellinus baumii Fruiting Body in Streptozotocin-Induced Diabetic Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1063586
Modern Language Association (MLA)
Wang, Wen-Han…[et al.]. Hypoglycemic Effect of Ethanol and Ethyl Acetate Extract of Phellinus baumii Fruiting Body in Streptozotocin-Induced Diabetic Mice. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1063586
American Medical Association (AMA)
Wang, Wen-Han& Wu, Fei-Hua& Yang, Yan& Wu, Na& Zhang, Jing-Song& Feng, Na…[et al.]. Hypoglycemic Effect of Ethanol and Ethyl Acetate Extract of Phellinus baumii Fruiting Body in Streptozotocin-Induced Diabetic Mice. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1063586
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063586
