Effect of Astaxanthin Supplementation on Salivary IgA, OxidativeStress, and Inflammation in Young Soccer Players
Joint Authors
Radojević-Škodrić, Sanja
Baralic, Ivana
Andjelkovic, Marija
Djordjevic, Brizita
Dikic, Nenad
Radivojevic, Nenad
Suzin-Zivkovic, Violeta
Pejic, Snezana
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-18
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The physiologic stress induced by physical activity is reflected in immune system perturbations, oxidative stress, muscle injury, and inflammation.
We investigated the effect of astaxanthin (Asx) supplementation on salivary IgA (sIgA) and oxidative stress status in plasma, along with changes in biochemical parameters and total/differential white cell counts.
Forty trained male soccer players were randomly assigned to Asx and placebo groups.
Asx group was supplemented with 4 mg of Asx.
Saliva and blood samples were collected at the baseline and after 90 days of supplementation in preexercise conditions.
We observed a rise of sIgA levels at rest after 90 days of Asx supplementation, which was accompanied with a decrease in prooxidant-antioxidant balance.
The plasma muscle enzymes levels were reduced significantly by Asx supplementation and by regular training.
The increase in neutrophil count and hs-CRP level was found only in placebo group, indicating a significant blunting of the systemic inflammatory response in the subjects taking Asx.
This study indicates that Asx supplementation improves sIgA response and attenuates muscle damage, thus preventing inflammation induced by rigorous physical training.
Our findings also point that Asx could show significant physiologic modulation in individuals with mucosal immunity impairment or under conditions of increased oxidative stress and inflammation.
American Psychological Association (APA)
Baralic, Ivana& Andjelkovic, Marija& Djordjevic, Brizita& Dikic, Nenad& Radivojevic, Nenad& Suzin-Zivkovic, Violeta…[et al.]. 2015. Effect of Astaxanthin Supplementation on Salivary IgA, OxidativeStress, and Inflammation in Young Soccer Players. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1063587
Modern Language Association (MLA)
Baralic, Ivana…[et al.]. Effect of Astaxanthin Supplementation on Salivary IgA, OxidativeStress, and Inflammation in Young Soccer Players. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1063587
American Medical Association (AMA)
Baralic, Ivana& Andjelkovic, Marija& Djordjevic, Brizita& Dikic, Nenad& Radivojevic, Nenad& Suzin-Zivkovic, Violeta…[et al.]. Effect of Astaxanthin Supplementation on Salivary IgA, OxidativeStress, and Inflammation in Young Soccer Players. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1063587
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063587