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The Consumption of Bicarbonate-Rich Mineral Water Improves Glycemic Control
Joint Authors
Murakami, Shinnosuke
Goto, Yasuaki
Ito, Kyo
Hayasaka, Shinya
Kurihara, Shigeo
Soga, Tomoyoshi
Fukuda, Shinji
Tomita, Masaru
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-21
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Hot spring water and natural mineral water have been therapeutically used to prevent or improve various diseases.
Specifically, consumption of bicarbonate-rich mineral water (BMW) has been reported to prevent or improve type 2 diabetes (T2D) in humans.
However, the molecular mechanisms of the beneficial effects behind mineral water consumption remain unclear.
To elucidate the molecular level effects of BMW consumption on glycemic control, blood metabolome analysis and fecal microbiome analysis were applied to the BMW consumption test.
During the study, 19 healthy volunteers drank 500 mL of commercially available tap water (TW) or BMW daily.
TW consumption periods and BMW consumption periods lasted for a week each and this cycle was repeated twice.
Biochemical tests indicated that serum glycoalbumin levels, one of the indexes of glycemic controls, decreased significantly after BMW consumption.
Metabolome analysis of blood samples revealed that 19 metabolites including glycolysis-related metabolites and 3 amino acids were significantly different between TW and BMW consumption periods.
Additionally, microbiome analysis demonstrated that composition of lean-inducible bacteria was increased after BMW consumption.
Our results suggested that consumption of BMW has the possible potential to prevent and/or improve T2D through the alterations of host metabolism and gut microbiota composition.
American Psychological Association (APA)
Murakami, Shinnosuke& Goto, Yasuaki& Ito, Kyo& Hayasaka, Shinya& Kurihara, Shigeo& Soga, Tomoyoshi…[et al.]. 2015. The Consumption of Bicarbonate-Rich Mineral Water Improves Glycemic Control. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1063650
Modern Language Association (MLA)
Murakami, Shinnosuke…[et al.]. The Consumption of Bicarbonate-Rich Mineral Water Improves Glycemic Control. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1063650
American Medical Association (AMA)
Murakami, Shinnosuke& Goto, Yasuaki& Ito, Kyo& Hayasaka, Shinya& Kurihara, Shigeo& Soga, Tomoyoshi…[et al.]. The Consumption of Bicarbonate-Rich Mineral Water Improves Glycemic Control. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1063650
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063650