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In Vitro Antimicrobial Activity and Effect on Biofilm Production of a White Grape Juice (Vitis vinifera) Extract
Joint Authors
Navarra, Michele
Filocamo, Angela
Bisignano, Carlo
Mandalari, Giuseppina
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-07
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
The aim of the present study was to evaluate the antimicrobial effect of a white grape juice extract (WGJe) against a range of Gram-positive and Gram-negative bacteria, yeasts, and the fungus Aspergillus niger.
WGJe was also tested on the production of bacterial biofilms in vitro.
Results.
WGJe inhibited in vitro most Gram-positive bacteria tested, Staphylococcus aureus ATCC 6538P being the most sensitive strain (MIC values of 3.9 μg/mL).
The effect was bactericidal at the concentration of 500 μg/mL.
Amongst the Gram-negative bacteria, Escherichia coli was the only susceptible strain (MIC and MBC of 2000 μg/mL).
No effect on the growth of Candida sp.
and the fungus Aspergillus niger was detected (MIC values > 2000 μg/mL).
WGJe inhibited the biofilms formation of E.
coli and Pseudomonas aeruginosa with a dose-dependent effect.
Conclusions.
WGJe exerted both bacteriostatic and bactericidal activity in vitro.
The presented results could be used to develop novel strategies for the treatment of skin infections and against potential respiratory pathogens.
American Psychological Association (APA)
Filocamo, Angela & Bisignano, Carlo & Mandalari, Giuseppina & Navarra, Michele. 2015. In Vitro Antimicrobial Activity and Effect on Biofilm Production of a White Grape Juice (Vitis vinifera) Extract. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1063688
Modern Language Association (MLA)
Filocamo, Angela…[et al.]. In Vitro Antimicrobial Activity and Effect on Biofilm Production of a White Grape Juice (Vitis vinifera) Extract. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1063688
American Medical Association (AMA)
Filocamo, Angela & Bisignano, Carlo & Mandalari, Giuseppina & Navarra, Michele. In Vitro Antimicrobial Activity and Effect on Biofilm Production of a White Grape Juice (Vitis vinifera) Extract. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1063688
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063688