The Immunomodulatory Effect of Acupoint Application for Childhood Asthma: A Systematic Review and Meta-Analysis
Joint Authors
Yin, Tao
Gao, Qian
Yang, Xiao Cun
Kong, Ling Jun
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-27
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
To evaluate the evidence on the immunomodulatory effect of acupoint application for childhood asthma.
Methods.
Five electronic databases through October 2014 were searched.
The risk of bias in eligible studies was assessed using the Cochrane Collaboration tool.
Standardised mean difference (SMD) and 95% confidence intervals (CI) of random-effects model were calculated.
And heterogeneity was assessed using the Cochran Q statistic and quantified with the I 2 index.
Results.
Six studies were included in our review.
The aggregated results suggested that acupoint application showed the beneficial effect for childhood asthma in improving IgA (SMD, −0.83; 95% CI −1.14 to −0.52; P < 0.00001 ), IgE (SMD, −0.52; 95% CI −0.76 to −0.29; P < 0.001 ), IgG (SMD, −1.17; 95% CI −1.61 to −0.74; P < 0.0001 ), IL-4 (SMD, −0.57; 95% CI −0.91 to −0.23; P = 0.0009 ), and IFN-γ (SMD, −0.38; 95% CI −0.71 to −0.04; P = 0.03 ) but not IgM (SMD, −0.40; 95% CI −0.98 to 0.18; P = 0.18 ).
And the effective dose of acupoint application may be 2–6 hours/time and a total of 3 times within 4 weeks.
Conclusions.
This review showed the positive evidence that acupoint application had the favorable immunomodulatory effect for childhood asthma.
However, more studies with long follow-up are warrant to confirm the current findings.
American Psychological Association (APA)
Yang, Xiao Cun& Yin, Tao& Gao, Qian& Kong, Ling Jun. 2015. The Immunomodulatory Effect of Acupoint Application for Childhood Asthma: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063730
Modern Language Association (MLA)
Yang, Xiao Cun…[et al.]. The Immunomodulatory Effect of Acupoint Application for Childhood Asthma: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1063730
American Medical Association (AMA)
Yang, Xiao Cun& Yin, Tao& Gao, Qian& Kong, Ling Jun. The Immunomodulatory Effect of Acupoint Application for Childhood Asthma: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063730
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063730