Acupuncture to Reduce HIV-Associated Inflammation
Joint Authors
Swanson, Barbara
Johnson, Angela
Adeyemi, Oluwatoyin
Sha, Beverly E.
Snell, Kimberly A.
Keithley, Joyce K.
Fogg, Lou
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
HIV infection is associated with systemic inflammation that can increase risk for cardiovascular events.
Acupuncture has been shown to have immunomodulatory effects and to improve symptoms in persons with inflammatory conditions.
Objective.
To test the anti-inflammatory effects of an acupuncture protocol that targets the cholinergic anti-inflammatory pathway (CAIP), a neural mechanism whose activation has been shown to reduce the release of proinflammatory cytokines, in persons with HIV-associated inflammation.
Design, Setting, Participants, and Interventions.
Double-blind, placebo-controlled clinical trial conducted in an outpatient clinic located in a medically underserved urban neighborhood.
Twenty-five clinically-stable HIV-infected persons on antiretroviral therapy were randomized to receive once weekly CAIP-based acupuncture or sham acupuncture.
Main Outcome Measures.
Outcomes included plasma concentrations of high sensitivity C-reactive protein and D-dimer and fasting lipids.
Results.
Twenty-five participants completed the protocol (treatment group n=12, control group n=13).
No adverse events related to the acupuncture protocol were observed.
Compared to baseline values, the two groups did not significantly differ in any outcome measures at the end of the acupuncture protocol.
Conclusions.
CAIP-based acupuncture did not favorably modulate inflammatory or lipid parameters.
Additional studies are warranted of CAIP-based protocols of different frequencies/durations.
American Psychological Association (APA)
Swanson, Barbara& Keithley, Joyce K.& Johnson, Angela& Fogg, Lou& Adeyemi, Oluwatoyin& Sha, Beverly E.…[et al.]. 2015. Acupuncture to Reduce HIV-Associated Inflammation. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063783
Modern Language Association (MLA)
Swanson, Barbara…[et al.]. Acupuncture to Reduce HIV-Associated Inflammation. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1063783
American Medical Association (AMA)
Swanson, Barbara& Keithley, Joyce K.& Johnson, Angela& Fogg, Lou& Adeyemi, Oluwatoyin& Sha, Beverly E.…[et al.]. Acupuncture to Reduce HIV-Associated Inflammation. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063783
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063783