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Ointment of Brassica oleracea var. capitata Matures the Extracellular Matrix in Skin Wounds of Wistar Rats
Joint Authors
Gonçalves, Reggiani Vilela
Sarandy, Mariáurea Matias
Novaes, Rômulo Dias
da Matta, Sérgio Luiz Pinto
Mezencio, Jose Mario da Silveira
da Silva, Marcelo Barreto
Zanuncio, José Cola
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-11
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Wound healing is a complex process that aims to restore damaged tissue.
Phytotherapeutics, such as cabbage, Brassica oleracea var.
capitata (Brassicaceae), and sunflower, Helianthus annuus L.
(Asteraceae) oil, are used as wound healers.
Five circular wounds, each 12 mm in diameter, were made in the dorsolateral region of each rat.
The animals were divided into four groups: balsam (B.
oleracea); ointment (B.
oleracea); sunflower oil (Helianthus annuus); control (saline solution 0.9%).
These products were applied daily for 20 days and every four days the tissues of different wounds were removed.
The wound contraction area, total collagen, types I and III collagen, glycosaminoglycans, and tissue cellularity were analyzed.
In the groups that received ointment and balsam there was reduction in the wound area on days 4, 8, 12, and 20.
Throughout the trial period, the balsam and ointment groups showed a higher amount of total collagen, type I collagen, and glycosaminoglycan compared to the others groups.
The rats in the groups treated with B.
oleracea var.
capitata showed a higher number of cells on days 8, 16, and 20.
B.
oleracea was effective in stimulating the maturation of collagen and increasing the cellularity, as also in improving the mechanical resistance of the newly formed tissue.
American Psychological Association (APA)
Sarandy, Mariáurea Matias& Novaes, Rômulo Dias& da Matta, Sérgio Luiz Pinto& Mezencio, Jose Mario da Silveira& da Silva, Marcelo Barreto& Zanuncio, José Cola…[et al.]. 2015. Ointment of Brassica oleracea var. capitata Matures the Extracellular Matrix in Skin Wounds of Wistar Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1063799
Modern Language Association (MLA)
Sarandy, Mariáurea Matias…[et al.]. Ointment of Brassica oleracea var. capitata Matures the Extracellular Matrix in Skin Wounds of Wistar Rats. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1063799
American Medical Association (AMA)
Sarandy, Mariáurea Matias& Novaes, Rômulo Dias& da Matta, Sérgio Luiz Pinto& Mezencio, Jose Mario da Silveira& da Silva, Marcelo Barreto& Zanuncio, José Cola…[et al.]. Ointment of Brassica oleracea var. capitata Matures the Extracellular Matrix in Skin Wounds of Wistar Rats. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1063799
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063799