Molecular and Functional Characterization of Bacopa monniera: A Retrospective Review
Joint Authors
Singh, Hemant K.
Rajan, Koilmani Emmanuvel
Preethi, Jayakumar
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-27
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Over the last 50 years, laboratories around the world analyzed the pharmacological effect of Bacopa monniera extract in different dimensions, especially as a nerve tonic and memory enhancer.
Studies in animal model evidenced that Bacopa treatment can attenuate dementia and enhances memory.
Further, they demonstrate that Bacopa primarily either acts via antioxidant mechanism (i.e., neuroprotection) or alters different neurotransmitters (serotonin (5-hydroxytryptamine, 5-HT), dopamine (DA), acetylcholine (ACh), γ-aminobutyric acid (GABA)) to execute the pharmacological effect.
Among them, 5-HT has been shown to fine tune the neural plasticity, which is a substrate for memory formation.
This review focuses on the studies which trace the effect of Bacopa treatment on serotonergic system and 5-HT mediated key molecular changes that are associated with memory formation.
American Psychological Association (APA)
Rajan, Koilmani Emmanuvel& Preethi, Jayakumar& Singh, Hemant K.. 2015. Molecular and Functional Characterization of Bacopa monniera: A Retrospective Review. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1063829
Modern Language Association (MLA)
Rajan, Koilmani Emmanuvel…[et al.]. Molecular and Functional Characterization of Bacopa monniera: A Retrospective Review. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1063829
American Medical Association (AMA)
Rajan, Koilmani Emmanuvel& Preethi, Jayakumar& Singh, Hemant K.. Molecular and Functional Characterization of Bacopa monniera: A Retrospective Review. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1063829
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063829