New Insights into the Role of Metformin Effects on Serum Omentin-1 Levels in Acute Myocardial Infarction: Cross-Sectional Study
Joint Authors
Alkuraishy, Hayder M.
Al-Gareeb, Ali I.
Source
Emergency Medicine International
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-23
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Serum omentin-1 level was low in the most types of ischemic heart disease compared to normal subjects; it also dependently correlated with coronary heart disease; thus, omentin-1 is regarded as a novel biomarker in IHD.
Objective.
The aim of the present study was to establish the links between omentin-1 and acute myocardial infarction in metformin patients.
Subjects and Methods.
A cross-sectional study was performed on eighty-five patients with type II DM and acute MI.
They are divided as follows: Group I, 62 patients with type II DM who received metformin prior to onset of acute MI; Group II, 23 patients with type II DM who did not receive metformin prior to onset of acute MI; and Group III, 30 normal healthy controls.
Venous blood was drawn from each participant for determination of lipid profile, plasma omentin-1, cardiac troponin-I (cTn-I) and other routine tests.
Results.
Patients that presented with acute MI that received metformin show a significant difference in all biochemical parameters ( p < 0.001 ); metformin increases serum omentin-1 level and decreases serum cardiac troponin-I level compared with control subjects and nonmetformin treated patients.
Conclusion.
Metformin pharmacotherapy increases omentin-1 serum levels and may be regarded as a potential agent in the prevention of the occurrences of acute MI in diabetic patients.
American Psychological Association (APA)
Alkuraishy, Hayder M.& Al-Gareeb, Ali I.. 2015. New Insights into the Role of Metformin Effects on Serum Omentin-1 Levels in Acute Myocardial Infarction: Cross-Sectional Study. Emergency Medicine International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063899
Modern Language Association (MLA)
Alkuraishy, Hayder M.& Al-Gareeb, Ali I.. New Insights into the Role of Metformin Effects on Serum Omentin-1 Levels in Acute Myocardial Infarction: Cross-Sectional Study. Emergency Medicine International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1063899
American Medical Association (AMA)
Alkuraishy, Hayder M.& Al-Gareeb, Ali I.. New Insights into the Role of Metformin Effects on Serum Omentin-1 Levels in Acute Myocardial Infarction: Cross-Sectional Study. Emergency Medicine International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063899
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063899