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The Significance of Serum CA-125 Elevation in Chinese Patients with Primary Budd-Chiari Syndrome: A Multicenter Study
Joint Authors
Xu, Hao
Cheng, De-lei
Lv, Wei-fu
Hua, Rong
Du, Hongtao
Zhang, Qing-qiao
Source
Gastroenterology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-15
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
To investigate the serum level of CA-125 and its corresponding clinical significance in Chinese patients with primary BCS.
Methods.
Serum CA-125 was measured in 243 patients with primary BCS receiving interventional treatment in the participating hospitals and in 120 healthy volunteers.
The correlation between serum CA-125 levels and ascites volume, liver function, and prognosis was analyzed.
Results.
Serum CA-125 was significantly elevated in BCS patients compared to healthy volunteers (P<0.001).
Higher levels of CA-125 were found in BCS patients with abnormal hepatic function and low serum albumin levels and in patients with high volume of ascites compared to patients without these abnormalities.
Serum CA-125 levels significantly correlated with ascites volume, serum level of alanine aminotransferase, aspartate aminotransferase, albumin, and Rotterdam BCS scores.
The follow-up study indicated that the survival rate and asymptomatic survival rate after interventional treatment were lower in BCS patients with serum CA-125 > 175 U/mL (P<0.05).
Conclusion.
Serum CA-125 was significantly higher in patients with primary BCS and had a positive correlation with the volume of ascites, severity of liver damage, and poor prognosis.
Thus the serum CA-125 levels may be used to estimate the severity and prognosis of BCS in Chinese patients.
American Psychological Association (APA)
Cheng, De-lei& Xu, Hao& Lv, Wei-fu& Hua, Rong& Du, Hongtao& Zhang, Qing-qiao. 2015. The Significance of Serum CA-125 Elevation in Chinese Patients with Primary Budd-Chiari Syndrome: A Multicenter Study. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063914
Modern Language Association (MLA)
Cheng, De-lei…[et al.]. The Significance of Serum CA-125 Elevation in Chinese Patients with Primary Budd-Chiari Syndrome: A Multicenter Study. Gastroenterology Research and Practice No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1063914
American Medical Association (AMA)
Cheng, De-lei& Xu, Hao& Lv, Wei-fu& Hua, Rong& Du, Hongtao& Zhang, Qing-qiao. The Significance of Serum CA-125 Elevation in Chinese Patients with Primary Budd-Chiari Syndrome: A Multicenter Study. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063914
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063914