CT Imaging Findings after Stereotactic Radiotherapy for Liver Tumors
Joint Authors
Brook, Olga R.
Thornton, Eavan
Mendiratta-Lala, Mishal
Mahadevan, Anand
Raptopoulos, Vassilious
Brook, Alexander
Najarian, Robert
Sheiman, Robert
Siewert, Bettina
Source
Gastroenterology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
To study radiological response to stereotactic radiotherapy for focal liver tumors.
Materials and Methods.
In this IRB-approved, HIPAA-compliant study CTs of 68 consecutive patients who underwent stereotactic radiotherapy for liver tumors between 01/2006 and 01/2010 were retrospectively reviewed.
Two independent reviewers evaluated lesion volume and enhancement pattern of the lesion and of juxtaposed liver parenchyma.
Results.
36 subjects with hepatocellular carcinoma (HCC), 25 with liver metastases, and seven with cholangiocarcinoma (CCC) were included in study.
Mean follow-up time was 5.6 ± 7.1 months for HCC, 6.4 ± 5.1 months for metastases, and 10.1 ± 4.8 months for the CCC.
Complete response was seen in 4/36 (11.1%) HCCs and 1/25 (4%) metastases.
Partial response (>30% decrease in long diameter) was seen in 25/36 (69%) HCCs, 14/25 (58%) metastases, and 7/7 (100%) of CCCs.
Partial response followed by local recurrence (>20% increase in long diameter from nadir) occurred in 2/36 (6%) HCCs and 4/25 (17%) metastases.
Liver parenchyma adjacent to the lesion demonstrated a prominent halo of delayed enhancement in 27/36 (78%) of HCCs, 19/21 (91%) of metastases, and 7/7 (100%) of CCCs.
Conclusion.
Sustainable radiological partial response to stereotactic radiotherapy is most frequent outcome seen in liver lesions.
Prominent halo of delayed enhancement of the adjacent liver is frequent finding.
American Psychological Association (APA)
Brook, Olga R.& Thornton, Eavan& Mendiratta-Lala, Mishal& Mahadevan, Anand& Raptopoulos, Vassilious& Brook, Alexander…[et al.]. 2015. CT Imaging Findings after Stereotactic Radiotherapy for Liver Tumors. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063916
Modern Language Association (MLA)
Brook, Olga R.…[et al.]. CT Imaging Findings after Stereotactic Radiotherapy for Liver Tumors. Gastroenterology Research and Practice No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1063916
American Medical Association (AMA)
Brook, Olga R.& Thornton, Eavan& Mendiratta-Lala, Mishal& Mahadevan, Anand& Raptopoulos, Vassilious& Brook, Alexander…[et al.]. CT Imaging Findings after Stereotactic Radiotherapy for Liver Tumors. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1063916
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063916