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Hepatitis B Virus-Related Glomerulonephritis: Not a Predominant Cause of Proteinuria in Korean Patients with Chronic Hepatitis B
Joint Authors
Yoo, Jeong-Ju
Lee, Jeong-Hoon
Yoon, Jung-Hwan
Lee, Minjong
Lee, Dong Hyeon
Cho, Yuri
Jang, Eun Sun
Cho, Eun Ju
Yu, Su Jong
Kim, Yoon Jun
Lee, Hyo-Suk
Source
Gastroenterology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background/Aims.
Hepatitis B virus (HBV) can form immune complexes which may result in various types of glomerulonephritis (GN).
However, proteinuria can occur because of other kidney diseases besides HBV-related GN (HBV-GN).
The aim of this study is to elucidate the causes of proteinuria and report on the clinical outcomes of HBV-GN.
Methods.
We reviewed the medical records of patients positive for serum hepatitis B surface antigen who underwent renal biopsies due to proteinuria at a tertiary medical center in Korea.
Results.
A total of 55 patients were included.
HBV-GN was diagnosed in 20 (36.4%) of the patients by confirming the presence of immune complexes (12 of 13 membranoproliferative glomerulonephritis, 7 of 8 membranous glomerulonephritis, and 1 of 13 immunoglobulin A nephropathy).
Twenty-one patients had other types of GN.
A total of 13 (65%) HBV-GN patients were treated with antiviral agents for a median of 11 months.
However, the degrees of proteinuria were not significantly reduced in the antiviral intervention group when compared to the control group.
Conclusions.
Proteinuria can be caused by various glomerular diseases and HBV-GN accounts for one-third of total GN cases.
Well-designed prospective study is needed to assess whether antiviral therapy against HBV infection may improve the prognosis of HBV-GN.
American Psychological Association (APA)
Yoo, Jeong-Ju& Lee, Jeong-Hoon& Yoon, Jung-Hwan& Lee, Minjong& Lee, Dong Hyeon& Cho, Yuri…[et al.]. 2015. Hepatitis B Virus-Related Glomerulonephritis: Not a Predominant Cause of Proteinuria in Korean Patients with Chronic Hepatitis B. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063917
Modern Language Association (MLA)
Yoo, Jeong-Ju…[et al.]. Hepatitis B Virus-Related Glomerulonephritis: Not a Predominant Cause of Proteinuria in Korean Patients with Chronic Hepatitis B. Gastroenterology Research and Practice No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1063917
American Medical Association (AMA)
Yoo, Jeong-Ju& Lee, Jeong-Hoon& Yoon, Jung-Hwan& Lee, Minjong& Lee, Dong Hyeon& Cho, Yuri…[et al.]. Hepatitis B Virus-Related Glomerulonephritis: Not a Predominant Cause of Proteinuria in Korean Patients with Chronic Hepatitis B. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063917
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063917