Helicobacter pylori Infection Is Associated with an Increased Risk of Hyperemesis Gravidarum: A Meta-Analysis
Joint Authors
Zhou, Xiaoying
Li, Lin
Li, Lingling
Gu, Huiyuan
Zhang, Guoxin
Xiao, Shuping
Source
Gastroenterology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-16
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Background.
Several studies have shown a possible involvement of Helicobacter pylori (H.
pylori) infection in individuals with hyperemesis gravidarum (HG), but the relationship remains controversial.
This meta-analysis was performed to validate and strengthen the association between HG and H.
pylori infection.
Methods.
PubMed, Embase, and Web of Science databases up to March 20, 2014, were searched to select studies on the prevalence of H.
pylori infection between pregnant women with HG and the normal pregnant control subjects.
Results.
Of the HG cases, 1289 (69.6%) were H.
pylori-positive; however, 1045 (46.2%) were H.
pylori-positive in control group.
Compared to the non-HG normal pregnant controls, infection rate of H.
pylori was significantly higher in pregnant women with HG (OR = 3.34, 95% CI: 2.32–4.81, P < 0.001 ).
Subgroup analysis indicated that H.
pylori infection was a risk factor of HG in Asia, Africa, and Oceania, especially in Africa (OR = 12.38, 95% CI: 7.12–21.54, P < 0.001 ).
Conclusions.
H.
pylori should be considered one of the risk factors of HG, especially in the developing countries.
H.
pylori eradication could be considered to relieve the symptoms of HG in some intractable cases.
American Psychological Association (APA)
Li, Lin& Li, Lingling& Zhou, Xiaoying& Xiao, Shuping& Gu, Huiyuan& Zhang, Guoxin. 2015. Helicobacter pylori Infection Is Associated with an Increased Risk of Hyperemesis Gravidarum: A Meta-Analysis. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1063948
Modern Language Association (MLA)
Li, Lin…[et al.]. Helicobacter pylori Infection Is Associated with an Increased Risk of Hyperemesis Gravidarum: A Meta-Analysis. Gastroenterology Research and Practice No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1063948
American Medical Association (AMA)
Li, Lin& Li, Lingling& Zhou, Xiaoying& Xiao, Shuping& Gu, Huiyuan& Zhang, Guoxin. Helicobacter pylori Infection Is Associated with an Increased Risk of Hyperemesis Gravidarum: A Meta-Analysis. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1063948
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063948