A Randomized Controlled Trial Evaluating a Low-Volume PEG Solution Plus Ascorbic Acid versus Standard PEG Solution in Bowel Preparation for Colonoscopy
Joint Authors
Bhatia, Vikram
Tajika, Masahiro
Tanaka, Tsutomu
Ishihara, Makoto
Mizuno, Nobumasa
Hara, Kazuo
Hijioka, Susumu
Imaoka, Hiroshi
Sato, Takamitsu
Yogi, Tatsuji
Tsutsumi, Hideharu
Fujiyoshi, Toshihisa
Hieda, Nobuhiro
Okuno, Nozomi
Yoshida, Tsukasa
Yatabe, Yasushi
Yamao, Kenji
Niwa, Yasumasa
Source
Gastroenterology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-15
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Evaluation of polyethylene glycol electrolyte lavage solution containing ascorbic acid (PEG-ASC) has been controversial in the point of its hyperosmolarity, especially in old population.
So we therefore designed the present study to compare the efficacy, acceptability, tolerability, and safety of 1.5 L PEG+ASC and 2 L standard PEG electrolyte solution (PEG-ELS), not only in the general population, but also in patients of advanced age.
Randomization was stratified by age (<70 years or 70> years), and hematological and biochemical parameters were compared in each age group, especially with respect to the safety profile of each regimen.
As a result, the 1.5-L PEG-ASC regimen had higher patient acceptability than the 2-L PEG-ELS regimen.
Tolerability, bowel cleansing, and safety were similar between regimens.
However, we demonstrated significant statistical changes in the hematological and biochemical parameters after taking bowel preparation solutions, not only in the PEG+ASC group, but also in the PEG-ELS group.
No significant differences in the safety profile were found between subjects aged less than 70 years and those aged 70 years or more; nevertheless, regardless of age, proper hydration is needed throughout the bowel preparation process.
American Psychological Association (APA)
Tajika, Masahiro& Tanaka, Tsutomu& Ishihara, Makoto& Mizuno, Nobumasa& Hara, Kazuo& Hijioka, Susumu…[et al.]. 2015. A Randomized Controlled Trial Evaluating a Low-Volume PEG Solution Plus Ascorbic Acid versus Standard PEG Solution in Bowel Preparation for Colonoscopy. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1063959
Modern Language Association (MLA)
Tajika, Masahiro…[et al.]. A Randomized Controlled Trial Evaluating a Low-Volume PEG Solution Plus Ascorbic Acid versus Standard PEG Solution in Bowel Preparation for Colonoscopy. Gastroenterology Research and Practice No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1063959
American Medical Association (AMA)
Tajika, Masahiro& Tanaka, Tsutomu& Ishihara, Makoto& Mizuno, Nobumasa& Hara, Kazuo& Hijioka, Susumu…[et al.]. A Randomized Controlled Trial Evaluating a Low-Volume PEG Solution Plus Ascorbic Acid versus Standard PEG Solution in Bowel Preparation for Colonoscopy. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1063959
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063959