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Outcomes and Risk Factors Associated with Clostridium difficile Diarrhea in Hospitalized Adult Patients
Joint Authors
Larentis, Daniela Zilio
dos Santos, Rodrigo Pires
Rosa, Regis Goulart
Goldani, Luciano Zubaran
Source
Gastroenterology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-25
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
The epidemiology of Clostridium difficile infection has changed over time.
Therefore, it is essential to monitor the characteristics of patients at risk of infection and factors associated with poor prognosis.
Objective.
To evaluate factors associated with C.
difficile infection and with poor prognosis in those with documented C.
difficile colitis.
Methods.
A retrospective case-control study of 75 patients with documented C.
difficile colitis and 75 controls with hospital-acquired diarrhea of other causes.
Stepwise multiple logistic regression was used to identify factors associated with C.
difficile infection among patients with hospital-acquired diarrhea.
Results.
Previous antibiotic treatment (odds ratio (OR), 13.3; 95% confidence interval (CI), 1.40–126.90), abdominal distension (OR, 3.85; 95% CI, 1.35–10.98), and fecal leukocytes (OR, 8.79; 95% CI, 1.41–54.61) are considered as predictors of C.
difficile colitis; anorexia was negatively associated with C.
difficile infection (OR, 0.15; 95% CI, 0.03–0.66).
Enteral tube feeding was independently associated with a composite outcome that included in-hospital mortality, intensive care unit admission, and treatment failure (OR, 3.75; 95%CI, 1.24–11.29).
Conclusions.
Previous antibiotic use and presence of fecal leukocytes in patients with hospital-acquired diarrhea are associated with C.
difficile colitis and enteral tube support with complications associated with C.
difficile colitis.
American Psychological Association (APA)
Larentis, Daniela Zilio& Rosa, Regis Goulart& dos Santos, Rodrigo Pires& Goldani, Luciano Zubaran. 2015. Outcomes and Risk Factors Associated with Clostridium difficile Diarrhea in Hospitalized Adult Patients. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063964
Modern Language Association (MLA)
Larentis, Daniela Zilio…[et al.]. Outcomes and Risk Factors Associated with Clostridium difficile Diarrhea in Hospitalized Adult Patients. Gastroenterology Research and Practice No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1063964
American Medical Association (AMA)
Larentis, Daniela Zilio& Rosa, Regis Goulart& dos Santos, Rodrigo Pires& Goldani, Luciano Zubaran. Outcomes and Risk Factors Associated with Clostridium difficile Diarrhea in Hospitalized Adult Patients. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1063964
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063964