Fecal Microbiota Transplantation Improves the Quality of Life in Patients with Inflammatory Bowel Disease
Joint Authors
Li, Jieshou
Wei, Yao
Zhu, Weiming
Gong, Jianfeng
Guo, Dong
Gu, Lili
Li, Ning
Source
Gastroenterology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-04
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
To determine the effect of fecal microbiota transplantation (FMT) on quality of life (QoL) in patients with inflammatory bowel disease (IBD).
Methods.
Fourteen IBD patients, including 11 Ulcerative colitis (UC) and 3 Crohn’s disease (CD), were treated with FMT via colonoscopy or nasojejunal tube infusion.
QoL was measured by IBD Questionnaire (IBDQ).
Disease activity and IBDQ were evaluated at enrollment and four weeks after treatment.
Patients’ attitude concerning the treatment was also investigated.
Results.
One patient was excluded due to intolerance.
All the other patients finished the study well.
Mean Mayo score in UC patients decreased significantly (5.80 ± 1.87 versus 1.50 ± 1.35, P < 0.01 ).
Mean IBDQ scores of both UC and CD patients increased (135.50 ± 27.18 versus 177.30 ± 20.88, P = 0.00063 , and 107.33 ± 9.45 versus 149.00 ± 20.07, P = 0.024 ) four weeks after fecal microbiota transplantation.
There was no correlation between the IBDQ score and Mayo score before and after FMT.
Patients refused to take FMT as treatment repeatedly in a short time.
Conlusions.
Fecal microbiota transplantation improves quality of life significantly in patients with inflammatory bowel disease.
American Psychological Association (APA)
Wei, Yao& Zhu, Weiming& Gong, Jianfeng& Guo, Dong& Gu, Lili& Li, Ning…[et al.]. 2015. Fecal Microbiota Transplantation Improves the Quality of Life in Patients with Inflammatory Bowel Disease. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1064010
Modern Language Association (MLA)
Wei, Yao…[et al.]. Fecal Microbiota Transplantation Improves the Quality of Life in Patients with Inflammatory Bowel Disease. Gastroenterology Research and Practice No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1064010
American Medical Association (AMA)
Wei, Yao& Zhu, Weiming& Gong, Jianfeng& Guo, Dong& Gu, Lili& Li, Ning…[et al.]. Fecal Microbiota Transplantation Improves the Quality of Life in Patients with Inflammatory Bowel Disease. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1064010
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1064010