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Peripheral Signals Mediate the Beneficial Effects of Gastric Surgery in Obesity
Joint Authors
Barja-Fernández, Silvia
Folgueira, Cintia
Castelao, Cecilia
Leis, Rosaura
Casanueva, Felipe F.
Seoane, Luisa M.
Source
Gastroenterology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-15
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Obesity is nowadays a public health problem both in the industrialized world and developing countries.
The different treatments to fight against obesity are not very successful with the exception of gastric surgery.
The mechanism behind the achievement of this procedure remains unclear although the modifications in the pattern of gastrointestinal hormones production appear to be responsible for the beneficial effect.
The gastrointestinal tract has emerged in the last time as an endocrine organ in charge of response to the different stimulus related to nutritional status by the modulation of more than 30 signals acting at central level to modulate food intake and body weight.
The production of some of these gastric derived signals has been proved to be altered in obesity (ghrelin, CCK, and GLP-1).
In fact, bariatric surgery modifies the production of both gastrointestinal and adipose tissue peripheral signals beyond the gut microbiota composition.
Through this paper the main peripheral signals altered in obesity will be reviewed together with their modifications after bariatric surgery.
American Psychological Association (APA)
Barja-Fernández, Silvia& Folgueira, Cintia& Castelao, Cecilia& Leis, Rosaura& Casanueva, Felipe F.& Seoane, Luisa M.. 2015. Peripheral Signals Mediate the Beneficial Effects of Gastric Surgery in Obesity. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1064038
Modern Language Association (MLA)
Barja-Fernández, Silvia…[et al.]. Peripheral Signals Mediate the Beneficial Effects of Gastric Surgery in Obesity. Gastroenterology Research and Practice No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1064038
American Medical Association (AMA)
Barja-Fernández, Silvia& Folgueira, Cintia& Castelao, Cecilia& Leis, Rosaura& Casanueva, Felipe F.& Seoane, Luisa M.. Peripheral Signals Mediate the Beneficial Effects of Gastric Surgery in Obesity. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1064038
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1064038