Narrow-Band Imaging Magnifying Endoscopy versus Lugol Chromoendoscopy with Pink-Color Sign Assessment in the Diagnosis of Superficial Esophageal Squamous Neoplasms: A Randomised Noninferiority Trial
Joint Authors
Goda, Kenichi
Dobashi, Akira
Yoshimura, Noboru
Kato, Masayuki
Aihara, Hiroyuki
Toyoizumi, Hirobumi
Ikegami, Masahiro
Kato, Tomohiro
Sumiyama, Kazuki
Tajiri, Hisao
Source
Gastroenterology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-01
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Previous studies have shown the high diagnostic accuracy of narrow-band imaging magnifying endoscopy (NBI-ME) and Lugol chromoendoscopy with pink-color sign assessment (LCE-PS) for superficial esophageal squamous cell carcinoma (SESCC).
However, there has been no controlled trial comparing these two diagnostic techniques.
We conducted a randomized noninferiority trial to compare the diagnostic accuracy of NBI-ME and LCE-PS.
We recruited patients with, or with a history of, squamous cell carcinoma in the head and neck region or in the esophagus.
They were randomly assigned to either NBI-ME or LCE-PS.
When lesions > 5 mm in diameter were found as brownish areas on NBI or as Lugol-voiding lesions (LVL), they were evaluated to determine whether they are SESCC on the basis of the findings of NBI-ME or PS in the LVL.
NBI-ME and LCE-PS were completed in 147 patients each.
There was no significant difference in all diagnostic values between the two techniques.
Compared with LCE-PS, NBI-ME showed a significantly shorter examination time but a larger number of misdiagnosed lesions especially in patients with many irregularly shaped multiform LVLs.
Compared with LCE-PS, NBI-ME might be similarly accurate and less invasive, but less reliable in patients with many LVLs, in the diagnosis of SESCC.
American Psychological Association (APA)
Goda, Kenichi& Dobashi, Akira& Yoshimura, Noboru& Kato, Masayuki& Aihara, Hiroyuki& Sumiyama, Kazuki…[et al.]. 2015. Narrow-Band Imaging Magnifying Endoscopy versus Lugol Chromoendoscopy with Pink-Color Sign Assessment in the Diagnosis of Superficial Esophageal Squamous Neoplasms: A Randomised Noninferiority Trial. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1064075
Modern Language Association (MLA)
Goda, Kenichi…[et al.]. Narrow-Band Imaging Magnifying Endoscopy versus Lugol Chromoendoscopy with Pink-Color Sign Assessment in the Diagnosis of Superficial Esophageal Squamous Neoplasms: A Randomised Noninferiority Trial. Gastroenterology Research and Practice No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1064075
American Medical Association (AMA)
Goda, Kenichi& Dobashi, Akira& Yoshimura, Noboru& Kato, Masayuki& Aihara, Hiroyuki& Sumiyama, Kazuki…[et al.]. Narrow-Band Imaging Magnifying Endoscopy versus Lugol Chromoendoscopy with Pink-Color Sign Assessment in the Diagnosis of Superficial Esophageal Squamous Neoplasms: A Randomised Noninferiority Trial. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1064075
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1064075