Clinical Outcomes and Quality of Life in Recipients of Livers Donated after Cardiac Death
Joint Authors
Parikh, Neehar D.
Skaro, Anton I.
Ladner, Daniela P.
Lyuksemburg, Vadim
Cahan, Joshua G.
Daud, Amna
Butt, Zeeshan
Source
Gastroenterology Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Donation after cardiac death (DCD) has expanded in the last decade in the US; however, DCD liver utilization has flattened in recent years due to poor outcomes.
We examined clinical and quality of life (QOL) outcomes of DCD recipients by conducting a retrospective and cross-sectional review of patients from 2003 to 2010.
We compared clinical outcomes of DCD recipients ( n = 60 ) to those of donation after brain death (DBD) liver recipients ( n = 669 ) during the same time period.
DCD recipients had significantly lower rates of 5-year graft survival ( P < 0.001 ) and a trend toward lower rates of 5-year patient survival ( P = 0.064 ) when compared to the DBD cohort.
In order to examine QOL outcomes in our cohorts, we administered the Short Form Liver Disease Quality of Life questionnaire to 30 DCD and 60 DBD recipients.
The DCD recipients reported lower generic and liver-specific QOL.
We further stratified the DCD cohort by the presence of ischemic cholangiopathy (IC).
Patients with IC reported lower QOL when compared to DBD recipients and those DCD recipients without IC ( P < 0.05 ).
While the results are consistent with clinical experience, this is the first report of QOL in DCD recipients using standardized measures.
These data can be used to guide future comparative effectiveness studies.
American Psychological Association (APA)
Parikh, Neehar D.& Skaro, Anton I.& Ladner, Daniela P.& Lyuksemburg, Vadim& Cahan, Joshua G.& Daud, Amna…[et al.]. 2015. Clinical Outcomes and Quality of Life in Recipients of Livers Donated after Cardiac Death. Gastroenterology Research and Practice،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1064085
Modern Language Association (MLA)
Parikh, Neehar D.…[et al.]. Clinical Outcomes and Quality of Life in Recipients of Livers Donated after Cardiac Death. Gastroenterology Research and Practice No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1064085
American Medical Association (AMA)
Parikh, Neehar D.& Skaro, Anton I.& Ladner, Daniela P.& Lyuksemburg, Vadim& Cahan, Joshua G.& Daud, Amna…[et al.]. Clinical Outcomes and Quality of Life in Recipients of Livers Donated after Cardiac Death. Gastroenterology Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1064085
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1064085